8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol

C20H13FN4O2S — CID 137285373

IUPAC8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol
SMILESOc1c(Cc2ccco2)nc2c(-c3ccnc(F)c3)nc(-c3cccs3)cn12
InChIInChI=1S/C20H13FN4O2S/c21-17-9-12(5-6-22-17)18-19-24-14(10-13-3-1-7-27-13)20(26)25(19)11-15(23-18)16-4-2-8-28-16/h1-9,11,26H,10H2
InChIKeyHLCPZCHWGCVCHV-UHFFFAOYSA-N
MW392.42 g/mol
LogP4.55
Rot. Bonds4

About 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol

8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol (PubChem CID 137285373) has the molecular formula C20H13FN4O2S and a molecular weight of 392.42 g/mol. Its IUPAC name is 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol.

Molecular Properties

Compound Name8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol
PubChem CID137285373
Molecular FormulaC20H13FN4O2S
Molecular Weight392.42 g/mol
Exact Mass392.07
IUPAC Name8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol
SMILESOc1c(Cc2ccco2)nc2c(-c3ccnc(F)c3)nc(-c3cccs3)cn12
InChIInChI=1S/C20H13FN4O2S/c21-17-9-12(5-6-22-17)18-19-24-14(10-13-3-1-7-27-13)20(26)25(19)11-15(23-18)16-4-2-8-28-16/h1-9,11,26H,10H2
InChIKeyHLCPZCHWGCVCHV-UHFFFAOYSA-N
XLogP4.55
TPSA76.45 Ų
H-Bond Donors1
H-Bond Acceptors7
Rotatable Bonds4
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500392.42
LogP ≤ 54.55
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 107

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

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Related Compounds

N-[8-[(3,4-difluorophenyl)methoxy]-2-ethylimidazo[1,2-a]pyridin-3-yl]-N-methylthiophene-2-carboxamide
CID 46942725
6-(2-Furyl)-3-(3-thienyl)imidazo [1,2-a]pyrazine
CID 117769709
8-benzyl-2-[(furan-2-yl)methyl]-6-phenyl-3H,7H-imidazo[1,2-a]pyrazin-3-one
CID 136008305
6-(3-amino-2-fluorophenyl)-8-((2-fluorophenyl)methyl)-2-((furan-2-yl)methyl)-3H,7H-imidazo(1,2-a)pyrazin-3-one
CID 146403983
Methyl 2-[[2-methyl-3-[methyl(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyridin-8-yl]oxymethyl]benzoate
CID 49790530
N-[2-ethyl-8-[2-(4-fluorophenyl)-2-oxoethoxy]imidazo[1,2-a]pyridin-3-yl]-N-methylthiophene-2-carboxamide
CID 49791166
1-(4-Fluorophenyl)-2-[2-methyl-3-[methyl(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyridin-8-yl]oxyethanone
CID 46948287
8-benzyl-6-(2-fluorophenyl)-2-(furan-2-ylmethyl)imidazo[1,2-a]pyrazin-3(7H)-one
CID 137314688
NanoLuc substrate 1
CID 146404021
NanoLuc substrate 2
CID 146404025
6-(2,3-difluorophenyl)-8-(2-fluorobenzyl)-2-((5-methylfuran-2-yl)methyl)imidazo[1,2-a]pyrazin-3(7H)-one
CID 166607090
8-benzyl-6-(3-fluorophenyl)-2-(furan-2-ylmethyl)imidazo[1,2-a]pyrazin-3(7H)-one
CID 166607091

Frequently Asked Questions

What is the IUPAC name of 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol?
The IUPAC name of 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol (CID 137285373) is 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol.
What is the SMILES notation for 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol?
The canonical SMILES for 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol is Oc1c(Cc2ccco2)nc2c(-c3ccnc(F)c3)nc(-c3cccs3)cn12.
What is the InChIKey of 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol?
The InChIKey is HLCPZCHWGCVCHV-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H13FN4O2S/c21-17-9-12(5-6-22-17)18-19-24-14(10-13-3-1-7-27-13)20(26)25(19)11-15(23-18)16-4-2-8-28-16/h1-9,11,26H,10H2.
What are the key properties of 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol?
8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol has a molecular weight of 392.42 g/mol, XLogP of 4.55, 4 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 8-(2-fluoro-4-pyridinyl)-2-(furan-2-ylmethyl)-6-thiophen-2-ylimidazo[1,2-a]pyrazin-3-ol is sourced from PubChem (CID 137285373), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).