About 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide
4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide (PubChem CID 137415346) has the molecular formula C25H31N7O4
and a molecular weight of 493.57 g/mol. Its IUPAC name is 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide.
Molecular Properties
| Compound Name | 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide |
| PubChem CID | 137415346 |
| Molecular Formula | C25H31N7O4 |
| Molecular Weight | 493.57 g/mol |
| Exact Mass | 493.24 |
| IUPAC Name | 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide |
| SMILES | C[C@@](N)(CO)C(=O)Nc1ccc(C(=O)Nc2ccn(-c3ccc(CNCCCN)cc3)c(=O)n2)cc1 |
| InChI | InChI=1S/C25H31N7O4/c1-25(27,16-33)23(35)29-19-7-5-18(6-8-19)22(34)30-21-11-14-32(24(36)31-21)20-9-3-17(4-10-20)15-28-13-2-12-26/h3-11,14,28,33H,2,12-13,15-16,26-27H2,1H3,(H,29,35)(H,30,31,34,36)/t25-/m1/s1 |
| InChIKey | ANFGLEZNJZIJLA-RUZDIDTESA-N |
| XLogP | 0.57 |
| TPSA | 177.39 Ų |
| H-Bond Donors | 6 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 11 |
| Heavy Atoms | 36 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 493.57 |
| LogP ≤ 5 | 0.57 |
| H-Bond Donors ≤ 5 | 6 |
| H-Bond Acceptors ≤ 10 | 9 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide?
The IUPAC name of 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide (CID 137415346) is 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide.
What is the SMILES notation for 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide?
The canonical SMILES for 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide is C[C@@](N)(CO)C(=O)Nc1ccc(C(=O)Nc2ccn(-c3ccc(CNCCCN)cc3)c(=O)n2)cc1.
What is the InChIKey of 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide?
The InChIKey is ANFGLEZNJZIJLA-RUZDIDTESA-N. The full InChI is InChI=1S/C25H31N7O4/c1-25(27,16-33)23(35)29-19-7-5-18(6-8-19)22(34)30-21-11-14-32(24(36)31-21)20-9-3-17(4-10-20)15-28-13-2-12-26/h3-11,14,28,33H,2,12-13,15-16,26-27H2,1H3,(H,29,35)(H,30,31,34,36)/t25-/m1/s1.
What are the key properties of 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide?
4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide has a molecular weight of 493.57 g/mol, XLogP of 0.57, 11 rotatable bonds, 6 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[[(2R)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[4-[(3-aminopropylamino)methyl]phenyl]-2-oxopyrimidin-4-yl]benzamide is sourced from PubChem (CID 137415346), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).