5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine

C17H12ClN5S — CID 137423726

IUPAC5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine
SMILESCc1cnc(-c2nc(N)cnc2-c2cc(Cl)c3ncccc3c2)s1
InChIInChI=1S/C17H12ClN5S/c1-9-7-22-17(24-9)16-15(21-8-13(19)23-16)11-5-10-3-2-4-20-14(10)12(18)6-11/h2-8H,1H3,(H2,19,23)
InChIKeyOMFQLZBRRFVKGG-UHFFFAOYSA-N
MW353.84 g/mol
LogP4.36
Rot. Bonds2

About 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine

5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine (PubChem CID 137423726) has the molecular formula C17H12ClN5S and a molecular weight of 353.84 g/mol. Its IUPAC name is 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine.

Molecular Properties

Compound Name5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine
PubChem CID137423726
Molecular FormulaC17H12ClN5S
Molecular Weight353.84 g/mol
Exact Mass353.05
IUPAC Name5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine
SMILESCc1cnc(-c2nc(N)cnc2-c2cc(Cl)c3ncccc3c2)s1
InChIInChI=1S/C17H12ClN5S/c1-9-7-22-17(24-9)16-15(21-8-13(19)23-16)11-5-10-3-2-4-20-14(10)12(18)6-11/h2-8H,1H3,(H2,19,23)
InChIKeyOMFQLZBRRFVKGG-UHFFFAOYSA-N
XLogP4.36
TPSA77.58 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds2
Heavy Atoms24
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500353.84
LogP ≤ 54.36
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

Analyze 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-(3-Methylphenyl)-5-(1,5-Naphthyridin-2-Yl)-1,3-Thiazol-2-Amine
CID 91885649
4-(3-Chlorophenyl)-5-(1,5-naphthyridin-2-yl)-1,3-thiazol-2-amine
CID 11473228
4-(3-Chloro-4-Fluorophenyl)-5-(1,5-Naphthyridin-2-Yl)-1,3-Thiazol-2-Amine
CID 91885650
N-(3-chloro-4-fluorophenyl)-8-methyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
CID 118736876
N-(4-chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
CID 118736891
N-(3-chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
CID 118736892
N-(2-chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
CID 118736893
N-pyridin-3-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
CID 118736909
5-(8-Methylquinolin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine
CID 45487443
N-(3-chloro-4-fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
CID 118736890
4-(3-Chloro-4-fluorophenyl)-5-(8-methyl-1,5-naphthyridin-2-yl)-1,3-thiazol-2-amine
CID 145963805
N-[4-(3-chlorophenyl)-5-(1,5-naphthyridin-2-yl)-1,3-thiazol-2-yl]acetamide
CID 145967414

Frequently Asked Questions

What is the IUPAC name of 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine?
The IUPAC name of 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine (CID 137423726) is 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine.
What is the SMILES notation for 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine?
The canonical SMILES for 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine is Cc1cnc(-c2nc(N)cnc2-c2cc(Cl)c3ncccc3c2)s1.
What is the InChIKey of 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine?
The InChIKey is OMFQLZBRRFVKGG-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H12ClN5S/c1-9-7-22-17(24-9)16-15(21-8-13(19)23-16)11-5-10-3-2-4-20-14(10)12(18)6-11/h2-8H,1H3,(H2,19,23).
What are the key properties of 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine?
5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine has a molecular weight of 353.84 g/mol, XLogP of 4.36, 2 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(8-chloroquinolin-6-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-amine is sourced from PubChem (CID 137423726), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).