About 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea
1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea (PubChem CID 140836926) has the molecular formula C27H30FN7O2
and a molecular weight of 503.58 g/mol. Its IUPAC name is 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea.
Molecular Properties
| Compound Name | 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea |
| PubChem CID | 140836926 |
| Molecular Formula | C27H30FN7O2 |
| Molecular Weight | 503.58 g/mol |
| Exact Mass | 503.24 |
| IUPAC Name | 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea |
| SMILES | CONC(=O)Nc1nn(C)cc1-c1ccc2ncc(-c3cc(C)cc(F)c3)c(N3CCC(N)CC3)c2c1 |
| InChI | InChI=1S/C27H30FN7O2/c1-16-10-18(12-19(28)11-16)22-14-30-24-5-4-17(13-21(24)25(22)35-8-6-20(29)7-9-35)23-15-34(2)32-26(23)31-27(36)33-37-3/h4-5,10-15,20H,6-9,29H2,1-3H3,(H2,31,32,33,36) |
| InChIKey | TWABTJXJXJDAMJ-UHFFFAOYSA-N |
| XLogP | 4.36 |
| TPSA | 110.33 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 37 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 503.58 |
| LogP ≤ 5 | 4.36 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea?
The IUPAC name of 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea (CID 140836926) is 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea.
What is the SMILES notation for 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea?
The canonical SMILES for 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea is CONC(=O)Nc1nn(C)cc1-c1ccc2ncc(-c3cc(C)cc(F)c3)c(N3CCC(N)CC3)c2c1.
What is the InChIKey of 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea?
The InChIKey is TWABTJXJXJDAMJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H30FN7O2/c1-16-10-18(12-19(28)11-16)22-14-30-24-5-4-17(13-21(24)25(22)35-8-6-20(29)7-9-35)23-15-34(2)32-26(23)31-27(36)33-37-3/h4-5,10-15,20H,6-9,29H2,1-3H3,(H2,31,32,33,36).
What are the key properties of 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea?
1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea has a molecular weight of 503.58 g/mol, XLogP of 4.36, 5 rotatable bonds, 3 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[4-[4-(4-aminopiperidin-1-yl)-3-(3-fluoro-5-methylphenyl)quinolin-6-yl]-1-methylpyrazol-3-yl]-3-methoxyurea is sourced from PubChem (CID 140836926), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).