About 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide
2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide (PubChem CID 140943447) has the molecular formula C13H14F5N7O
and a molecular weight of 379.29 g/mol. Its IUPAC name is 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide.
Molecular Properties
| Compound Name | 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide |
| PubChem CID | 140943447 |
| Molecular Formula | C13H14F5N7O |
| Molecular Weight | 379.29 g/mol |
| Exact Mass | 379.12 |
| IUPAC Name | 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide |
| SMILES | CNC(=O)C(F)(F)n1cc(Nc2ncc(C(F)(F)F)c(NC)n2)c(C)n1 |
| InChI | InChI=1S/C13H14F5N7O/c1-6-8(5-25(24-6)13(17,18)10(26)20-3)22-11-21-4-7(12(14,15)16)9(19-2)23-11/h4-5H,1-3H3,(H,20,26)(H2,19,21,22,23) |
| InChIKey | ZCFSCKCWHJPLGK-UHFFFAOYSA-N |
| XLogP | 2.08 |
| TPSA | 96.76 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 26 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 379.29 |
| LogP ≤ 5 | 2.08 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide?
The IUPAC name of 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide (CID 140943447) is 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide.
What is the SMILES notation for 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide?
The canonical SMILES for 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide is CNC(=O)C(F)(F)n1cc(Nc2ncc(C(F)(F)F)c(NC)n2)c(C)n1.
What is the InChIKey of 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide?
The InChIKey is ZCFSCKCWHJPLGK-UHFFFAOYSA-N. The full InChI is InChI=1S/C13H14F5N7O/c1-6-8(5-25(24-6)13(17,18)10(26)20-3)22-11-21-4-7(12(14,15)16)9(19-2)23-11/h4-5H,1-3H3,(H,20,26)(H2,19,21,22,23).
What are the key properties of 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide?
2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide has a molecular weight of 379.29 g/mol, XLogP of 2.08, 5 rotatable bonds, 3 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 2,2-difluoro-N-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]acetamide is sourced from PubChem (CID 140943447), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).