About (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone
(3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone (PubChem CID 141127939) has the molecular formula C13H22F2N4O
and a molecular weight of 288.34 g/mol. Its IUPAC name is (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone.
Molecular Properties
| Compound Name | (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone |
| PubChem CID | 141127939 |
| Molecular Formula | C13H22F2N4O |
| Molecular Weight | 288.34 g/mol |
| Exact Mass | 288.18 |
| IUPAC Name | (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone |
| SMILES | O=C([C@@H]1C[C@H](N2CCNCC2)CN1)N1CCC(F)(F)C1 |
| InChI | InChI=1S/C13H22F2N4O/c14-13(15)1-4-19(9-13)12(20)11-7-10(8-17-11)18-5-2-16-3-6-18/h10-11,16-17H,1-9H2/t10-,11-/m0/s1 |
| InChIKey | OSSGZAWRBISFKG-QWRGUYRKSA-N |
| XLogP | -0.51 |
| TPSA | 47.61 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 20 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 288.34 |
| LogP ≤ 5 | -0.51 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone?
The IUPAC name of (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone (CID 141127939) is (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone.
What is the SMILES notation for (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone?
The canonical SMILES for (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone is O=C([C@@H]1C[C@H](N2CCNCC2)CN1)N1CCC(F)(F)C1.
What is the InChIKey of (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone?
The InChIKey is OSSGZAWRBISFKG-QWRGUYRKSA-N. The full InChI is InChI=1S/C13H22F2N4O/c14-13(15)1-4-19(9-13)12(20)11-7-10(8-17-11)18-5-2-16-3-6-18/h10-11,16-17H,1-9H2/t10-,11-/m0/s1.
What are the key properties of (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone?
(3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone has a molecular weight of 288.34 g/mol, XLogP of -0.51, 2 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-piperazin-1-ylpyrrolidin-2-yl]methanone is sourced from PubChem (CID 141127939), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).