N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine

C15H16F3N5 — CID 141399085

IUPACN-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine
SMILESFC(F)(F)c1cnc(Nc2ccc(C3CCNCC3)nc2)nc1
InChIInChI=1S/C15H16F3N5/c16-15(17,18)11-7-21-14(22-8-11)23-12-1-2-13(20-9-12)10-3-5-19-6-4-10/h1-2,7-10,19H,3-6H2,(H,21,22,23)
InChIKeySROGDIWFBJTLJR-UHFFFAOYSA-N
MW323.32 g/mol
LogP3.10
Rot. Bonds3

About N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine

N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine (PubChem CID 141399085) has the molecular formula C15H16F3N5 and a molecular weight of 323.32 g/mol. Its IUPAC name is N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine.

Molecular Properties

Compound NameN-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine
PubChem CID141399085
Molecular FormulaC15H16F3N5
Molecular Weight323.32 g/mol
Exact Mass323.14
IUPAC NameN-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine
SMILESFC(F)(F)c1cnc(Nc2ccc(C3CCNCC3)nc2)nc1
InChIInChI=1S/C15H16F3N5/c16-15(17,18)11-7-21-14(22-8-11)23-12-1-2-13(20-9-12)10-3-5-19-6-4-10/h1-2,7-10,19H,3-6H2,(H,21,22,23)
InChIKeySROGDIWFBJTLJR-UHFFFAOYSA-N
XLogP3.10
TPSA62.73 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms23
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500323.32
LogP ≤ 53.10
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

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Related Compounds

2-pyrrolidin-3-yl-5-(trifluoromethyl)pyridine;hydrochloride
CID 171371651
2-(azetidin-3-yl)-5-(trifluoromethyl)pyridine
CID 71302276
5-[(2,6-difluoro-3-methoxy-5-methylphenyl)methoxy]-N-(6-piperidin-4-yl-3-pyridinyl)pyrimidin-2-amine
CID 122605373
2-piperidin-4-yl-5-[4-(trifluoromethyl)phenyl]pyrazine
CID 95823573
2-piperidin-4-yl-4-(trifluoromethyl)pyridine
CID 18413985
N-[(3R)-pyrrolidin-3-yl]-5-(trifluoromethyl)pyrimidin-2-amine
CID 125498682
1-[(6-piperidin-4-yl-3-pyridinyl)amino]piperidine-2,6-dione
CID 175756538
4-fluoro-3-methoxy-N-methyl-5-[[2-[(6-piperidin-4-yl-3-pyridinyl)amino]pyrimidin-5-yl]oxymethyl]benzamide
CID 90435728
3-piperidin-4-yl-N-[6-(trifluoromethyl)-3-pyridinyl]-1H-indol-6-amine
CID 53493779
6-hydroxy-5-[(6-piperidin-4-yl-3-pyridinyl)amino]piperidin-2-one
CID 166899953
N-(4-piperidin-4-ylsulfonylphenyl)-5-[2-[3-(trifluoromethyl)phenyl]ethenyl]pyrimidin-2-amine
CID 69441709
N-[(3R)-piperidin-3-yl]-5-(trifluoromethyl)pyrimidin-2-amine
CID 168827322

Frequently Asked Questions

What is the IUPAC name of N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine?
The IUPAC name of N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine (CID 141399085) is N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine.
What is the SMILES notation for N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine?
The canonical SMILES for N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine is FC(F)(F)c1cnc(Nc2ccc(C3CCNCC3)nc2)nc1.
What is the InChIKey of N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine?
The InChIKey is SROGDIWFBJTLJR-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H16F3N5/c16-15(17,18)11-7-21-14(22-8-11)23-12-1-2-13(20-9-12)10-3-5-19-6-4-10/h1-2,7-10,19H,3-6H2,(H,21,22,23).
What are the key properties of N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine?
N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine has a molecular weight of 323.32 g/mol, XLogP of 3.10, 3 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-(6-piperidin-4-yl-3-pyridinyl)-5-(trifluoromethyl)pyrimidin-2-amine is sourced from PubChem (CID 141399085), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).