About 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane
4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane (PubChem CID 142251997) has the molecular formula C36H44ClF2N5O
and a molecular weight of 636.23 g/mol. Its IUPAC name is 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane.
Molecular Properties
| Compound Name | 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane |
| PubChem CID | 142251997 |
| Molecular Formula | C36H44ClF2N5O |
| Molecular Weight | 636.23 g/mol |
| Exact Mass | 635.32 |
| IUPAC Name | 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane |
| SMILES | C=C/N=C1\C(=C)C(Cn2ccnc2C)=Cc2cc(Cl)ccc2C1C1CCN(C(=O)Nc2ccc(C(F)F)cc2)CC1.CC.CC |
| InChI | InChI=1S/C32H32ClF2N5O.2C2H6/c1-4-36-30-20(2)25(19-40-16-13-37-21(40)3)17-24-18-26(33)7-10-28(24)29(30)22-11-14-39(15-12-22)32(41)38-27-8-5-23(6-9-27)31(34)35;2*1-2/h4-10,13,16-18,22,29,31H,1-2,11-12,14-15,19H2,3H3,(H,38,41);2*1-2H3/b36-30+;; |
| InChIKey | NNJRHEPBGDQQOJ-MINSIKMNSA-N |
| XLogP | 10.10 |
| TPSA | 62.52 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 45 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 636.23 |
| LogP ≤ 5 | 10.10 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'imine_1', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane?
The IUPAC name of 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane (CID 142251997) is 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane.
What is the SMILES notation for 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane?
The canonical SMILES for 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane is C=C/N=C1\C(=C)C(Cn2ccnc2C)=Cc2cc(Cl)ccc2C1C1CCN(C(=O)Nc2ccc(C(F)F)cc2)CC1.CC.CC.
What is the InChIKey of 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane?
The InChIKey is NNJRHEPBGDQQOJ-MINSIKMNSA-N. The full InChI is InChI=1S/C32H32ClF2N5O.2C2H6/c1-4-36-30-20(2)25(19-40-16-13-37-21(40)3)17-24-18-26(33)7-10-28(24)29(30)22-11-14-39(15-12-22)32(41)38-27-8-5-23(6-9-27)31(34)35;2*1-2/h4-10,13,16-18,22,29,31H,1-2,11-12,14-15,19H2,3H3,(H,38,41);2*1-2H3/b36-30+;;.
What are the key properties of 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane?
4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane has a molecular weight of 636.23 g/mol, XLogP of 10.10, 6 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[2-chloro-6-ethenylimino-7-methylidene-8-[(2-methylimidazol-1-yl)methyl]-5H-benzo[7]annulen-5-yl]-N-[4-(difluoromethyl)phenyl]piperidine-1-carboxamide;ethane is sourced from PubChem (CID 142251997), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).