2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide

C18H12F3N5O2 — CID 142297980

IUPAC2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide
SMILESCOc1cc(C(F)(F)F)c2ccc3nc(C(=O)Nc4ccncc4)cn3c2n1
InChIInChI=1S/C18H12F3N5O2/c1-28-15-8-12(18(19,20)21)11-2-3-14-24-13(9-26(14)16(11)25-15)17(27)23-10-4-6-22-7-5-10/h2-9H,1H3,(H,22,23,27)
InChIKeySFKVPDWMUJFBHV-UHFFFAOYSA-N
MW387.32 g/mol
LogP3.56
Rot. Bonds3

About 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide

2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide (PubChem CID 142297980) has the molecular formula C18H12F3N5O2 and a molecular weight of 387.32 g/mol. Its IUPAC name is 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide.

Molecular Properties

Compound Name2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide
PubChem CID142297980
Molecular FormulaC18H12F3N5O2
Molecular Weight387.32 g/mol
Exact Mass387.09
IUPAC Name2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide
SMILESCOc1cc(C(F)(F)F)c2ccc3nc(C(=O)Nc4ccncc4)cn3c2n1
InChIInChI=1S/C18H12F3N5O2/c1-28-15-8-12(18(19,20)21)11-2-3-14-24-13(9-26(14)16(11)25-15)17(27)23-10-4-6-22-7-5-10/h2-9H,1H3,(H,22,23,27)
InChIKeySFKVPDWMUJFBHV-UHFFFAOYSA-N
XLogP3.56
TPSA81.41 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds3
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500387.32
LogP ≤ 53.56
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

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Related Compounds

2-Methoxy-6,7-Dimethyl-9-(4-Methylpyridin-3-Yl)imidazo[1,5-A]pyrido[3,2-E]pyrazine
CID 42629702
12-Methoxy-5,7-dimethyl-3-pyridin-3-yl-2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
CID 42629350
12-Methoxy-5,7-dimethyl-3-(2-methyl-3-pyridinyl)-2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
CID 56648681
12-Methoxy-5,7-dimethyl-3-(6-methyl-3-pyridinyl)-2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
CID 56648682
12-Methoxy-5,7-dimethyl-3-(3-methyl-4-pyridinyl)-2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
CID 56648684
2-(2-ethoxyphenyl)-8-methyl-3H-purino[9,8-a]pyridin-4-one
CID 135964375
1-amino-N-[2-(4-methoxyphenyl)ethyl]pyrazino[1,2-a]benzimidazole-3-carboxamide
CID 168297407
(2S)-N-[5-[2-(6-methoxy-3-pyridinyl)-7-methylimidazo[1,2-a]pyridin-3-yl]-6-[2-(1-methylisoquinolin-6-yl)ethynyl]-2-pyridinyl]-2-(methylamino)propanamide
CID 118863000
3-amino-N-(3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl)-6-(6-methoxy-3-(trifluoromethyl)pyridin-2-yl)pyrazine-2-carboxamide
CID 118875823
N-(trans-4-fluoropiperidin-3-yl)-8-(2-(2,2,2-trifluoroethoxy)phenyl)imidazo[1,2-a]pyridine-2-carboxamide
CID 162763666
N-(4-fluoropyridin-3-yl)-8-(2-(2,2,2-trifluoroethoxy)phenyl)imidazo[1,2-a]pyridine-2-carboxamide
CID 162763684
N-(4-methylpyridin-3-yl)-8-(2-(2,2,2-trifluoroethoxy)phenyl)imidazo[1,2-a]pyridine-2-carboxamide
CID 162763705

Frequently Asked Questions

What is the IUPAC name of 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide?
The IUPAC name of 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide (CID 142297980) is 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide.
What is the SMILES notation for 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide?
The canonical SMILES for 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide is COc1cc(C(F)(F)F)c2ccc3nc(C(=O)Nc4ccncc4)cn3c2n1.
What is the InChIKey of 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide?
The InChIKey is SFKVPDWMUJFBHV-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H12F3N5O2/c1-28-15-8-12(18(19,20)21)11-2-3-14-24-13(9-26(14)16(11)25-15)17(27)23-10-4-6-22-7-5-10/h2-9H,1H3,(H,22,23,27).
What are the key properties of 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide?
2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide has a molecular weight of 387.32 g/mol, XLogP of 3.56, 3 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-methoxy-N-pyridin-4-yl-4-(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide is sourced from PubChem (CID 142297980), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).