5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide

C23H19F3N6O2 — CID 142412294

IUPAC5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide
SMILESNc1nc2cc(-c3cnc(C4CC4)c(C(=O)NCc4cccc(OC(F)(F)F)c4)c3)ccn2n1
InChIInChI=1S/C23H19F3N6O2/c24-23(25,26)34-17-3-1-2-13(8-17)11-29-21(33)18-9-16(12-28-20(18)14-4-5-14)15-6-7-32-19(10-15)30-22(27)31-32/h1-3,6-10,12,14H,4-5,11H2,(H2,27,31)(H,29,33)
InChIKeyWJRDFFRXYYEIOF-UHFFFAOYSA-N
MW468.44 g/mol
LogP4.08
Rot. Bonds6

About 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide

5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide (PubChem CID 142412294) has the molecular formula C23H19F3N6O2 and a molecular weight of 468.44 g/mol. Its IUPAC name is 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide.

Molecular Properties

Compound Name5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide
PubChem CID142412294
Molecular FormulaC23H19F3N6O2
Molecular Weight468.44 g/mol
Exact Mass468.15
IUPAC Name5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide
SMILESNc1nc2cc(-c3cnc(C4CC4)c(C(=O)NCc4cccc(OC(F)(F)F)c4)c3)ccn2n1
InChIInChI=1S/C23H19F3N6O2/c24-23(25,26)34-17-3-1-2-13(8-17)11-29-21(33)18-9-16(12-28-20(18)14-4-5-14)15-6-7-32-19(10-15)30-22(27)31-32/h1-3,6-10,12,14H,4-5,11H2,(H2,27,31)(H,29,33)
InChIKeyWJRDFFRXYYEIOF-UHFFFAOYSA-N
XLogP4.08
TPSA107.43 Ų
H-Bond Donors2
H-Bond Acceptors7
Rotatable Bonds6
Heavy Atoms34
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500468.44
LogP ≤ 54.08
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 107

Analyze 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-methoxy-6-methyl-N-[2-[3-(trifluoromethoxy)phenyl]ethyl]pyridine-3-carboxamide
CID 152535099
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-[(2-cyclopentyloxy-6-fluorophenyl)methyl]-2-methoxypyridine-3-carboxamide
CID 135304812
2-[4-([1,2,4]triazolo[1,5-a]pyridin-7-yl)phenyl]-N-[[3-(trifluoromethoxy)phenyl]methyl]acetamide
CID 176939255
5-(2-amino-1,3-benzothiazol-6-yl)-2-methoxy-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide
CID 155146663
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-[(2-cyclopentyloxy-3-pyridinyl)methyl]-2-methoxypyridine-3-carboxamide
CID 152703549
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-2-methoxypyridine-3-carboxamide
CID 142412280
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-[[2-[[(2R)-2-bicyclo[2.2.1]heptanyl]oxy]-6-fluorophenyl]methyl]-2-methoxypyridine-3-carboxamide
CID 153302459
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-[[4-fluoro-2-(oxolan-2-yloxy)phenyl]methyl]-2-methoxypyridine-3-carboxamide
CID 153302348
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-ethoxy-N-[[1-(2-fluorophenyl)cyclopropyl]methyl]pyridine-3-carboxamide
CID 150121188
[5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-methoxy-3-pyridinyl]-[3-[(4-methoxyphenyl)methyl]piperidin-1-yl]methanone
CID 150349405
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-[(2-cyclopentyloxy-6-fluorophenyl)methyl]pyridine-3-carboxamide
CID 135304962
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-[3-(4-fluorophenyl)-3-hydroxypropyl]-2-methoxypyridine-3-carboxamide
CID 135304837

Frequently Asked Questions

What is the IUPAC name of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide?
The IUPAC name of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide (CID 142412294) is 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide.
What is the SMILES notation for 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide?
The canonical SMILES for 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide is Nc1nc2cc(-c3cnc(C4CC4)c(C(=O)NCc4cccc(OC(F)(F)F)c4)c3)ccn2n1.
What is the InChIKey of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide?
The InChIKey is WJRDFFRXYYEIOF-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H19F3N6O2/c24-23(25,26)34-17-3-1-2-13(8-17)11-29-21(33)18-9-16(12-28-20(18)14-4-5-14)15-6-7-32-19(10-15)30-22(27)31-32/h1-3,6-10,12,14H,4-5,11H2,(H2,27,31)(H,29,33).
What are the key properties of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide?
5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide has a molecular weight of 468.44 g/mol, XLogP of 4.08, 6 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-2-cyclopropyl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyridine-3-carboxamide is sourced from PubChem (CID 142412294), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).