N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide

C21H19N5O3 — CID 142447291

IUPACN-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide
SMILESCc1cc2c(cc1-c1cc3cc(NC(=O)C4CC4)ncc3c(N)n1)C(O)C(=O)N2
InChIInChI=1S/C21H19N5O3/c1-9-4-15-13(18(27)21(29)25-15)7-12(9)16-5-11-6-17(26-20(28)10-2-3-10)23-8-14(11)19(22)24-16/h4-8,10,18,27H,2-3H2,1H3,(H2,22,24)(H,25,29)(H,23,26,28)
InChIKeyOGIWLBXNECVNOM-UHFFFAOYSA-N
MW389.42 g/mol
LogP2.52
Rot. Bonds3

About N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide

N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide (PubChem CID 142447291) has the molecular formula C21H19N5O3 and a molecular weight of 389.42 g/mol. Its IUPAC name is N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide.

Molecular Properties

Compound NameN-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide
PubChem CID142447291
Molecular FormulaC21H19N5O3
Molecular Weight389.42 g/mol
Exact Mass389.15
IUPAC NameN-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide
SMILESCc1cc2c(cc1-c1cc3cc(NC(=O)C4CC4)ncc3c(N)n1)C(O)C(=O)N2
InChIInChI=1S/C21H19N5O3/c1-9-4-15-13(18(27)21(29)25-15)7-12(9)16-5-11-6-17(26-20(28)10-2-3-10)23-8-14(11)19(22)24-16/h4-8,10,18,27H,2-3H2,1H3,(H2,22,24)(H,25,29)(H,23,26,28)
InChIKeyOGIWLBXNECVNOM-UHFFFAOYSA-N
XLogP2.52
TPSA130.23 Ų
H-Bond Donors4
H-Bond Acceptors6
Rotatable Bonds3
Heavy Atoms29
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500389.42
LogP ≤ 52.52
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 106

Analyze N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[7-[6-[(1R)-1-hydroxyethyl]-4-methyl-3-pyridinyl]isoquinolin-3-yl]cyclopropanecarboxamide
CID 57411327
N-[7-[6-[(1S)-1-hydroxyethyl]-4-methyl-3-pyridinyl]isoquinolin-3-yl]cyclopropanecarboxamide
CID 57411328
N-(7-(6-(hydroxymethyl)-4-methylpyridin-3-yl)isoquinolin-3-yl)cyclopropanecarboxamide
CID 68095262
N-[7-[5-(hydroxymethyl)-2-methylphenyl]-2,6-naphthyridin-3-yl]cyclopropanecarboxamide
CID 71114966
N-[7-[6-[(1R)-1-hydroxypropyl]-4-methyl-3-pyridinyl]isoquinolin-3-yl]cyclopropanecarboxamide
CID 71115036
N-[7-[6-[(1S)-1-hydroxypropyl]-4-methyl-3-pyridinyl]isoquinolin-3-yl]cyclopropanecarboxamide
CID 71115049
(2S)-2-fluoro-N-[7-[2-[(1R)-1-hydroxyethyl]-4-methyl-3-pyridinyl]isoquinolin-3-yl]cyclopropane-1-carboxamide
CID 71128091
(2S)-2-fluoro-N-[7-[2-[(1S)-1-hydroxyethyl]-4-methyl-3-pyridinyl]isoquinolin-3-yl]cyclopropane-1-carboxamide
CID 71128094
N-(7-(5-(hydroxymethyl)-2-methylpyridin-3-yl)isoquinolin-3-yl)cyclopropanecarboxamide
CID 67974857
N-[7-[2-(hydroxymethyl)-5-methyl-4-pyridinyl]isoquinolin-3-yl]cyclopropanecarboxamide
CID 71115082
cis-N-[8-amino-6-[4-(hydroxymethyl)-3-pyridyl]-3-isoquinolyl]-2-fluoro-cyclopropane-1-carboxamide
CID 135343386
cis-N-(8-amino-6-(4-ethyl-6-(hydroxymethyl)pyridin-3-yl)isoquinolin-3-yl)-2-fluorocyclopropane-1-carboxamide
CID 135343508

Frequently Asked Questions

What is the IUPAC name of N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide?
The IUPAC name of N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide (CID 142447291) is N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide.
What is the SMILES notation for N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide?
The canonical SMILES for N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide is Cc1cc2c(cc1-c1cc3cc(NC(=O)C4CC4)ncc3c(N)n1)C(O)C(=O)N2.
What is the InChIKey of N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide?
The InChIKey is OGIWLBXNECVNOM-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H19N5O3/c1-9-4-15-13(18(27)21(29)25-15)7-12(9)16-5-11-6-17(26-20(28)10-2-3-10)23-8-14(11)19(22)24-16/h4-8,10,18,27H,2-3H2,1H3,(H2,22,24)(H,25,29)(H,23,26,28).
What are the key properties of N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide?
N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide has a molecular weight of 389.42 g/mol, XLogP of 2.52, 3 rotatable bonds, 4 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide is sourced from PubChem (CID 142447291), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).