(2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide

C22H21FN2O2 — CID 143454842

IUPAC(2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide
SMILESCc1ccccc1C[C@@H](C)C(=O)Nc1ccc(-n2ccccc2=O)cc1F
InChIInChI=1S/C22H21FN2O2/c1-15-7-3-4-8-17(15)13-16(2)22(27)24-20-11-10-18(14-19(20)23)25-12-6-5-9-21(25)26/h3-12,14,16H,13H2,1-2H3,(H,24,27)/t16-/m1/s1
InChIKeyZHHDEPZVWQIJIS-MRXNPFEDSA-N
MW364.42 g/mol
LogP4.10
Rot. Bonds5

About (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide

(2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide (PubChem CID 143454842) has the molecular formula C22H21FN2O2 and a molecular weight of 364.42 g/mol. Its IUPAC name is (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide.

Molecular Properties

Compound Name(2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide
PubChem CID143454842
Molecular FormulaC22H21FN2O2
Molecular Weight364.42 g/mol
Exact Mass364.16
IUPAC Name(2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide
SMILESCc1ccccc1C[C@@H](C)C(=O)Nc1ccc(-n2ccccc2=O)cc1F
InChIInChI=1S/C22H21FN2O2/c1-15-7-3-4-8-17(15)13-16(2)22(27)24-20-11-10-18(14-19(20)23)25-12-6-5-9-21(25)26/h3-12,14,16H,13H2,1-2H3,(H,24,27)/t16-/m1/s1
InChIKeyZHHDEPZVWQIJIS-MRXNPFEDSA-N
XLogP4.10
TPSA51.10 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds5
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500364.42
LogP ≤ 54.10
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

Analyze (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

dimethyl (E)-2-[2-fluoro-4-(2-oxo-1-pyridinyl)anilino]but-2-enedioate
CID 168566903
2-[[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]carbamoyl]-3-(hydroxymethyl)cyclopropane-1-carboxylic acid
CID 141145339
ethyl 4-[[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]carbamoyl]pyrrolidine-3-carboxylate
CID 69114943
trans-(1S,2S)-2-[[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]carbamoyl]-1-methylcyclopropane-1-carboxylic acid
CID 66882265
(3R,4R)-4-N-(4-chlorophenyl)-3-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-1-(1-fluoropropan-2-yl)pyrrolidine-3,4-dicarboxamide
CID 69047032
methyl (3R,4R)-1-(2,2-difluoroethyl)-4-[[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]carbamoyl]pyrrolidine-3-carboxylate
CID 59800165
(1R,3S,4S)-3-amino-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-4-hydroxycyclopentane-1-carboxamide
CID 68687455
(4S)-1-[2-[2-fluoro-4-(2-oxo-1-pyridinyl)anilino]-2-oxoethyl]-4-methylpyrrolidine-2-carboxamide
CID 173100301
5-chloro-2-[[3-(2-fluorophenyl)-2-methylpropanoyl]amino]benzoic acid
CID 141008013
5-chloro-N-[(3R)-1-[1-[2-fluoro-4-(2-oxo-1-pyridinyl)anilino]-1-oxopropan-2-yl]pyrrolidin-3-yl]thiophene-2-carboxamide
CID 58748343
cis-(2S,3R)-3-N-(4-chlorophenyl)-1-N-ethyl-2-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-1-methylcyclopropane-1,2,3-tricarboxamide
CID 143223851
(1S,3S,4S)-3-amino-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-4-methoxycyclopentane-1-carboxamide
CID 68686790

Frequently Asked Questions

What is the IUPAC name of (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide?
The IUPAC name of (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide (CID 143454842) is (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide.
What is the SMILES notation for (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide?
The canonical SMILES for (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide is Cc1ccccc1C[C@@H](C)C(=O)Nc1ccc(-n2ccccc2=O)cc1F.
What is the InChIKey of (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide?
The InChIKey is ZHHDEPZVWQIJIS-MRXNPFEDSA-N. The full InChI is InChI=1S/C22H21FN2O2/c1-15-7-3-4-8-17(15)13-16(2)22(27)24-20-11-10-18(14-19(20)23)25-12-6-5-9-21(25)26/h3-12,14,16H,13H2,1-2H3,(H,24,27)/t16-/m1/s1.
What are the key properties of (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide?
(2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide has a molecular weight of 364.42 g/mol, XLogP of 4.10, 5 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-2-methyl-3-(2-methylphenyl)propanamide is sourced from PubChem (CID 143454842), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).