N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide

C14H14F5NO — CID 143468785

IUPACN-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide
SMILESC[C@H](c1cc(F)cc(F)c1)N(C)C(=O)C1(C(F)(F)F)CC1
InChIInChI=1S/C14H14F5NO/c1-8(9-5-10(15)7-11(16)6-9)20(2)12(21)13(3-4-13)14(17,18)19/h5-8H,3-4H2,1-2H3/t8-/m1/s1
InChIKeyCZXCJEUGNOLKGY-MRVPVSSYSA-N
MW307.26 g/mol
LogP3.83
Rot. Bonds3

About N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide

N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide (PubChem CID 143468785) has the molecular formula C14H14F5NO and a molecular weight of 307.26 g/mol. Its IUPAC name is N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide.

Molecular Properties

Compound NameN-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide
PubChem CID143468785
Molecular FormulaC14H14F5NO
Molecular Weight307.26 g/mol
Exact Mass307.10
IUPAC NameN-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide
SMILESC[C@H](c1cc(F)cc(F)c1)N(C)C(=O)C1(C(F)(F)F)CC1
InChIInChI=1S/C14H14F5NO/c1-8(9-5-10(15)7-11(16)6-9)20(2)12(21)13(3-4-13)14(17,18)19/h5-8H,3-4H2,1-2H3/t8-/m1/s1
InChIKeyCZXCJEUGNOLKGY-MRVPVSSYSA-N
XLogP3.83
TPSA20.31 Ų
H-Bond Donors
H-Bond Acceptors1
Rotatable Bonds3
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500307.26
LogP ≤ 53.83
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 101

Analyze N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[(3,5-difluorophenyl)methyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide
CID 143468788
1-amino-N-[1-(4-fluorophenyl)ethyl]-N-methylcyclobutane-1-carboxamide
CID 81173083
carboxy-[1-(3,5-difluorophenyl)ethyl]carbamic acid
CID 66955357
4-amino-N-[1-(4-fluorophenyl)ethyl]-N-methyloxane-4-carboxamide
CID 115294203
N-[1-(3,5-difluorophenyl)ethyl]-N-[3-(2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl)prop-2-enyl]-1-(trifluoromethyl)cyclopropane-1-carboxamide
CID 76771541
2-(3,5-difluorophenyl)-2-(dimethylamino)acetic acid
CID 106531816
1-(3-fluorophenyl)-N-methyl-N-(1-phenylethyl)cyclobutane-1-carboxamide
CID 112812988
N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-[2-oxo-2-[[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]amino]ethyl]-1-(trifluoromethyl)cyclopropane-1-carboxamide
CID 59581323
tert-butyl 4-[(1S)-1-(3,5-difluorophenyl)ethyl]-4-fluoropiperidine-1-carboxylate
CID 163385674
1-amino-N-methyl-N-(1-pyridin-4-ylethyl)cyclopropane-1-carboxamide
CID 65463841
N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-[4-(4-fluorophenyl)piperidin-4-yl]-N-methylacetamide
CID 87665080
N-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-3-(4-fluorophenyl)-3-(4-fluoropiperidin-4-yl)-N-methylpropanamide
CID 87881125

Frequently Asked Questions

What is the IUPAC name of N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide?
The IUPAC name of N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide (CID 143468785) is N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide.
What is the SMILES notation for N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide?
The canonical SMILES for N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide is C[C@H](c1cc(F)cc(F)c1)N(C)C(=O)C1(C(F)(F)F)CC1.
What is the InChIKey of N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide?
The InChIKey is CZXCJEUGNOLKGY-MRVPVSSYSA-N. The full InChI is InChI=1S/C14H14F5NO/c1-8(9-5-10(15)7-11(16)6-9)20(2)12(21)13(3-4-13)14(17,18)19/h5-8H,3-4H2,1-2H3/t8-/m1/s1.
What are the key properties of N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide?
N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide has a molecular weight of 307.26 g/mol, XLogP of 3.83, 3 rotatable bonds, 0 hydrogen bond donors, and 1 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1R)-1-(3,5-difluorophenyl)ethyl]-N-methyl-1-(trifluoromethyl)cyclopropane-1-carboxamide is sourced from PubChem (CID 143468785), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).