2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane

C21H14F7N3 — CID 143803661

IUPAC2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane
SMILESCF.Fc1ccc(Nc2c(-c3c(F)cccc3F)nc3cccc(C(F)(F)F)n23)cc1
InChIInChI=1S/C20H11F6N3.CH3F/c21-11-7-9-12(10-8-11)27-19-18(17-13(22)3-1-4-14(17)23)28-16-6-2-5-15(29(16)19)20(24,25)26;1-2/h1-10,27H;1H3
InChIKeyYYXXATVKMWMYMZ-UHFFFAOYSA-N
MW441.35 g/mol
LogP6.77
Rot. Bonds3

About 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane

2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane (PubChem CID 143803661) has the molecular formula C21H14F7N3 and a molecular weight of 441.35 g/mol. Its IUPAC name is 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane.

Molecular Properties

Compound Name2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane
PubChem CID143803661
Molecular FormulaC21H14F7N3
Molecular Weight441.35 g/mol
Exact Mass441.11
IUPAC Name2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane
SMILESCF.Fc1ccc(Nc2c(-c3c(F)cccc3F)nc3cccc(C(F)(F)F)n23)cc1
InChIInChI=1S/C20H11F6N3.CH3F/c21-11-7-9-12(10-8-11)27-19-18(17-13(22)3-1-4-14(17)23)28-16-6-2-5-15(29(16)19)20(24,25)26;1-2/h1-10,27H;1H3
InChIKeyYYXXATVKMWMYMZ-UHFFFAOYSA-N
XLogP6.77
TPSA29.33 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds3
Heavy Atoms31
Complexity—

Lipinski Rule of Five

1 violation

RuleValue
MW ≤ 500441.35
LogP ≤ 56.77
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-(2-chloro-6-methylphenyl)-2-(2,6-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-2-(2,6-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,6-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;2-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine
CID 158447438
2-(2-fluoro-5-methylphenyl)-N-(4-fluorophenyl)-5-methylimidazo[1,2-a]pyridin-3-amine
CID 59579086
N-(4-fluorophenyl)-2-(3-fluoro-4-pyridinyl)-5-methylimidazo[1,2-a]pyridin-3-amine
CID 59579146
2-(2-chloro-6-fluorophenyl)-N-cyclohexyl-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine
CID 59578915
6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-3-phenylimidazo[2,1-b][1,3]thiazol-5-amine
CID 59579215
6-(2-fluoro-6-iodophenyl)-N-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine
CID 70832089
6-(2-chloro-6-fluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine
CID 59578837
2-(2,4-difluorophenyl)-5-ethyl-N-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-methylimidazo[1,2-a]pyridin-3-amine
CID 143803790
5-methyl-N,2-bis(4-methylphenyl)imidazo[1,2-a]pyridin-3-amine
CID 3515709
3-cyclohexa-1,3-dien-1-yl-6-(2,6-difluorophenyl)-N-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-5-amine
CID 71016477
2-(4-chlorophenyl)-5-methyl-N-(4-methylphenyl)imidazo[1,2-a]pyridin-3-amine
CID 7338705
5-methyl-N-(4-methylphenyl)-2-(5-methylthiophen-2-yl)imidazo[1,2-a]pyridin-3-amine
CID 20857276

Frequently Asked Questions

What is the IUPAC name of 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane?
The IUPAC name of 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane (CID 143803661) is 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane.
What is the SMILES notation for 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane?
The canonical SMILES for 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane is CF.Fc1ccc(Nc2c(-c3c(F)cccc3F)nc3cccc(C(F)(F)F)n23)cc1.
What is the InChIKey of 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane?
The InChIKey is YYXXATVKMWMYMZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H11F6N3.CH3F/c21-11-7-9-12(10-8-11)27-19-18(17-13(22)3-1-4-14(17)23)28-16-6-2-5-15(29(16)19)20(24,25)26;1-2/h1-10,27H;1H3.
What are the key properties of 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane?
2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane has a molecular weight of 441.35 g/mol, XLogP of 6.77, 3 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2,6-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;fluoromethane is sourced from PubChem (CID 143803661), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).