About 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine
4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine (PubChem CID 144739899) has the molecular formula C12H14ClF2N3O
and a molecular weight of 289.71 g/mol. Its IUPAC name is 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine.
Molecular Properties
| Compound Name | 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine |
| PubChem CID | 144739899 |
| Molecular Formula | C12H14ClF2N3O |
| Molecular Weight | 289.71 g/mol |
| Exact Mass | 289.08 |
| IUPAC Name | 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine |
| SMILES | FC1(F)CC1Cc1nc(Cl)cc(N2CCOCC2)n1 |
| InChI | InChI=1S/C12H14ClF2N3O/c13-9-6-11(18-1-3-19-4-2-18)17-10(16-9)5-8-7-12(8,14)15/h6,8H,1-5,7H2 |
| InChIKey | NOFDLIQHQRZUTF-UHFFFAOYSA-N |
| XLogP | 2.16 |
| TPSA | 38.25 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 19 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 289.71 |
| LogP ≤ 5 | 2.16 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine?
The IUPAC name of 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine (CID 144739899) is 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine.
What is the SMILES notation for 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine?
The canonical SMILES for 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine is FC1(F)CC1Cc1nc(Cl)cc(N2CCOCC2)n1.
What is the InChIKey of 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine?
The InChIKey is NOFDLIQHQRZUTF-UHFFFAOYSA-N. The full InChI is InChI=1S/C12H14ClF2N3O/c13-9-6-11(18-1-3-19-4-2-18)17-10(16-9)5-8-7-12(8,14)15/h6,8H,1-5,7H2.
What are the key properties of 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine?
4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine has a molecular weight of 289.71 g/mol, XLogP of 2.16, 3 rotatable bonds, 0 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[6-chloro-2-[(2,2-difluorocyclopropyl)methyl]pyrimidin-4-yl]morpholine is sourced from PubChem (CID 144739899), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).