About [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone
[5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone (PubChem CID 144878300) has the molecular formula C22H20ClF2N3O3S
and a molecular weight of 479.94 g/mol. Its IUPAC name is [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone.
Molecular Properties
| Compound Name | [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone |
| PubChem CID | 144878300 |
| Molecular Formula | C22H20ClF2N3O3S |
| Molecular Weight | 479.94 g/mol |
| Exact Mass | 479.09 |
| IUPAC Name | [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone |
| SMILES | COc1ccc(F)c(C(=O)c2ccc(-c3cc(Cl)c(OC)c(CN(N)/C=C\N)c3)s2)c1F |
| InChI | InChI=1S/C22H20ClF2N3O3S/c1-30-16-4-3-15(24)19(20(16)25)21(29)18-6-5-17(32-18)12-9-13(11-28(27)8-7-26)22(31-2)14(23)10-12/h3-10H,11,26-27H2,1-2H3/b8-7- |
| InChIKey | BHZQWIQTINKQHB-FPLPWBNLSA-N |
| XLogP | 4.70 |
| TPSA | 90.81 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 479.94 |
| LogP ≤ 5 | 4.70 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'hydrazine', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone?
The IUPAC name of [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone (CID 144878300) is [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone.
What is the SMILES notation for [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone?
The canonical SMILES for [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone is COc1ccc(F)c(C(=O)c2ccc(-c3cc(Cl)c(OC)c(CN(N)/C=C\N)c3)s2)c1F.
What is the InChIKey of [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone?
The InChIKey is BHZQWIQTINKQHB-FPLPWBNLSA-N. The full InChI is InChI=1S/C22H20ClF2N3O3S/c1-30-16-4-3-15(24)19(20(16)25)21(29)18-6-5-17(32-18)12-9-13(11-28(27)8-7-26)22(31-2)14(23)10-12/h3-10H,11,26-27H2,1-2H3/b8-7-.
What are the key properties of [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone?
[5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone has a molecular weight of 479.94 g/mol, XLogP of 4.70, 8 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for [5-[3-[[amino-[(Z)-2-aminoethenyl]amino]methyl]-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-methoxyphenyl)methanone is sourced from PubChem (CID 144878300), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).