About 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine
5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine (PubChem CID 144886527) has the molecular formula C23H22F2N6S
and a molecular weight of 452.53 g/mol. Its IUPAC name is 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine.
Molecular Properties
| Compound Name | 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine |
| PubChem CID | 144886527 |
| Molecular Formula | C23H22F2N6S |
| Molecular Weight | 452.53 g/mol |
| Exact Mass | 452.16 |
| IUPAC Name | 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine |
| SMILES | C=C(Nc1nc(-c2cc(C3=NCC=C3)n(Cc3ccccc3F)n2)ncc1F)C(C)SC |
| InChI | InChI=1S/C23H22F2N6S/c1-14(15(2)32-3)28-22-18(25)12-27-23(29-22)20-11-21(19-9-6-10-26-19)31(30-20)13-16-7-4-5-8-17(16)24/h4-9,11-12,15H,1,10,13H2,2-3H3,(H,27,28,29) |
| InChIKey | HFFWGLDULINKPW-UHFFFAOYSA-N |
| XLogP | 4.70 |
| TPSA | 67.99 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 452.53 |
| LogP ≤ 5 | 4.70 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
Analyze 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine with MolForge
Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.
Launch Full Analysis
Frequently Asked Questions
What is the IUPAC name of 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine?
The IUPAC name of 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine (CID 144886527) is 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine.
What is the SMILES notation for 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine?
The canonical SMILES for 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine is C=C(Nc1nc(-c2cc(C3=NCC=C3)n(Cc3ccccc3F)n2)ncc1F)C(C)SC.
What is the InChIKey of 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine?
The InChIKey is HFFWGLDULINKPW-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H22F2N6S/c1-14(15(2)32-3)28-22-18(25)12-27-23(29-22)20-11-21(19-9-6-10-26-19)31(30-20)13-16-7-4-5-8-17(16)24/h4-9,11-12,15H,1,10,13H2,2-3H3,(H,27,28,29).
What are the key properties of 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine?
5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine has a molecular weight of 452.53 g/mol, XLogP of 4.70, 8 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(2H-pyrrol-5-yl)pyrazol-3-yl]-N-(3-methylsulfanylbut-1-en-2-yl)pyrimidin-4-amine is sourced from PubChem (CID 144886527), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).