About N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide
N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide (PubChem CID 145444039) has the molecular formula C19H21F3N6O2S
and a molecular weight of 454.48 g/mol. Its IUPAC name is N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide.
Molecular Properties
| Compound Name | N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide |
| PubChem CID | 145444039 |
| Molecular Formula | C19H21F3N6O2S |
| Molecular Weight | 454.48 g/mol |
| Exact Mass | 454.14 |
| IUPAC Name | N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide |
| SMILES | CNS(=O)(=O)c1ccc2c(-c3nc(N[C@H]4CCCNC4)ncc3C(F)(F)F)c[nH]c2c1 |
| InChI | InChI=1S/C19H21F3N6O2S/c1-23-31(29,30)12-4-5-13-14(9-25-16(13)7-12)17-15(19(20,21)22)10-26-18(28-17)27-11-3-2-6-24-8-11/h4-5,7,9-11,23-25H,2-3,6,8H2,1H3,(H,26,27,28)/t11-/m0/s1 |
| InChIKey | YOKJZKNQSMSTEA-NSHDSACASA-N |
| XLogP | 2.72 |
| TPSA | 111.80 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 454.48 |
| LogP ≤ 5 | 2.72 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide?
The IUPAC name of N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide (CID 145444039) is N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide.
What is the SMILES notation for N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide?
The canonical SMILES for N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide is CNS(=O)(=O)c1ccc2c(-c3nc(N[C@H]4CCCNC4)ncc3C(F)(F)F)c[nH]c2c1.
What is the InChIKey of N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide?
The InChIKey is YOKJZKNQSMSTEA-NSHDSACASA-N. The full InChI is InChI=1S/C19H21F3N6O2S/c1-23-31(29,30)12-4-5-13-14(9-25-16(13)7-12)17-15(19(20,21)22)10-26-18(28-17)27-11-3-2-6-24-8-11/h4-5,7,9-11,23-25H,2-3,6,8H2,1H3,(H,26,27,28)/t11-/m0/s1.
What are the key properties of N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide?
N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide has a molecular weight of 454.48 g/mol, XLogP of 2.72, 5 rotatable bonds, 4 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-indole-6-sulfonamide is sourced from PubChem (CID 145444039), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).