About 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide
3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide (PubChem CID 145970598) has the molecular formula C18H15FN4O3
and a molecular weight of 354.30 g/mol. Its IUPAC name is 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide.
Molecular Properties
| Compound Name | 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide |
| PubChem CID | 145970598 |
| Molecular Formula | C18H15FN4O3 |
| Molecular Weight | 354.30 g/mol |
| Exact Mass | 354.11 |
| IUPAC Name | 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide |
| SMILES | C1=CC(=CC=C1CNC(=O)C2=CC(=NN2)C3=CC=C(C=C3)F)C(=O)NO |
| InChI | InChI=1S/C18H15FN4O3/c19-14-7-5-12(6-8-14)15-9-16(22-21-15)18(25)20-10-11-1-3-13(4-2-11)17(24)23-26/h1-9,26H,10H2,(H,20,25)(H,21,22)(H,23,24) |
| InChIKey | PANMZVOPZWWAGR-UHFFFAOYSA-N |
| XLogP | 1.90 |
| TPSA | 107.00 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 26 |
| Complexity | 491 |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 354.30 |
| LogP ≤ 5 | 1.90 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide?
The IUPAC name of 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide (CID 145970598) is 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide.
What is the SMILES notation for 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide?
The canonical SMILES for 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide is C1=CC(=CC=C1CNC(=O)C2=CC(=NN2)C3=CC=C(C=C3)F)C(=O)NO.
What is the InChIKey of 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide?
The InChIKey is PANMZVOPZWWAGR-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H15FN4O3/c19-14-7-5-12(6-8-14)15-9-16(22-21-15)18(25)20-10-11-1-3-13(4-2-11)17(24)23-26/h1-9,26H,10H2,(H,20,25)(H,21,22)(H,23,24).
What are the key properties of 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide?
3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide has a molecular weight of 354.30 g/mol, XLogP of 1.90, 5 rotatable bonds, 4 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(4-fluorophenyl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrazole-5-carboxamide is sourced from PubChem (CID 145970598), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).