About N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide
N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide (PubChem CID 146113855) has the molecular formula C15H16F3N5O2
and a molecular weight of 355.32 g/mol. Its IUPAC name is N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide.
Molecular Properties
| Compound Name | N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide |
| PubChem CID | 146113855 |
| Molecular Formula | C15H16F3N5O2 |
| Molecular Weight | 355.32 g/mol |
| Exact Mass | 355.13 |
| IUPAC Name | N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide |
| SMILES | O=C(N[C@@H]1CC(Cn2cccn2)C[C@H]1O)c1cc(C(F)(F)F)ncn1 |
| InChI | InChI=1S/C15H16F3N5O2/c16-15(17,18)13-6-11(19-8-20-13)14(25)22-10-4-9(5-12(10)24)7-23-3-1-2-21-23/h1-3,6,8-10,12,24H,4-5,7H2,(H,22,25)/t9?,10-,12-/m1/s1 |
| InChIKey | UIHIDSFPBUDZEI-GTFYECCDSA-N |
| XLogP | 1.26 |
| TPSA | 92.93 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 25 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 355.32 |
| LogP ≤ 5 | 1.26 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide?
The IUPAC name of N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide (CID 146113855) is N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide.
What is the SMILES notation for N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide?
The canonical SMILES for N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide is O=C(N[C@@H]1CC(Cn2cccn2)C[C@H]1O)c1cc(C(F)(F)F)ncn1.
What is the InChIKey of N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide?
The InChIKey is UIHIDSFPBUDZEI-GTFYECCDSA-N. The full InChI is InChI=1S/C15H16F3N5O2/c16-15(17,18)13-6-11(19-8-20-13)14(25)22-10-4-9(5-12(10)24)7-23-3-1-2-21-23/h1-3,6,8-10,12,24H,4-5,7H2,(H,22,25)/t9?,10-,12-/m1/s1.
What are the key properties of N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide?
N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide has a molecular weight of 355.32 g/mol, XLogP of 1.26, 4 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1R,2R)-2-hydroxy-4-(pyrazol-1-ylmethyl)cyclopentyl]-6-(trifluoromethyl)pyrimidine-4-carboxamide is sourced from PubChem (CID 146113855), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).