About [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone
[4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone (PubChem CID 146153976) has the molecular formula C15H21F2N5O
and a molecular weight of 325.36 g/mol. Its IUPAC name is [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone.
Molecular Properties
| Compound Name | [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone |
| PubChem CID | 146153976 |
| Molecular Formula | C15H21F2N5O |
| Molecular Weight | 325.36 g/mol |
| Exact Mass | 325.17 |
| IUPAC Name | [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone |
| SMILES | Cc1nc(C(=O)N2CCC(F)(F)C2)nc(N2CC[C@@H](N)C2)c1C |
| InChI | InChI=1S/C15H21F2N5O/c1-9-10(2)19-12(14(23)22-6-4-15(16,17)8-22)20-13(9)21-5-3-11(18)7-21/h11H,3-8,18H2,1-2H3/t11-/m1/s1 |
| InChIKey | KDMHWWACWDGMJJ-LLVKDONJSA-N |
| XLogP | 1.11 |
| TPSA | 75.35 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 23 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 325.36 |
| LogP ≤ 5 | 1.11 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone?
The IUPAC name of [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone (CID 146153976) is [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone.
What is the SMILES notation for [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone?
The canonical SMILES for [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone is Cc1nc(C(=O)N2CCC(F)(F)C2)nc(N2CC[C@@H](N)C2)c1C.
What is the InChIKey of [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone?
The InChIKey is KDMHWWACWDGMJJ-LLVKDONJSA-N. The full InChI is InChI=1S/C15H21F2N5O/c1-9-10(2)19-12(14(23)22-6-4-15(16,17)8-22)20-13(9)21-5-3-11(18)7-21/h11H,3-8,18H2,1-2H3/t11-/m1/s1.
What are the key properties of [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone?
[4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone has a molecular weight of 325.36 g/mol, XLogP of 1.11, 2 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for [4-[(3R)-3-aminopyrrolidin-1-yl]-5,6-dimethylpyrimidin-2-yl]-(3,3-difluoropyrrolidin-1-yl)methanone is sourced from PubChem (CID 146153976), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).