1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea

C19H22N4O2S — CID 146366370

IUPAC1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea
SMILESO=C(Nc1csc(-c2ccc(C3=CCOC3)cc2)n1)NC1CCCNC1
InChIInChI=1S/C19H22N4O2S/c24-19(21-16-2-1-8-20-10-16)23-17-12-26-18(22-17)14-5-3-13(4-6-14)15-7-9-25-11-15/h3-7,12,16,20H,1-2,8-11H2,(H2,21,23,24)
InChIKeyGTBVJFIGZJFBSY-UHFFFAOYSA-N
MW370.48 g/mol
LogP3.10
Rot. Bonds4

About 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea

1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea (PubChem CID 146366370) has the molecular formula C19H22N4O2S and a molecular weight of 370.48 g/mol. Its IUPAC name is 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea.

Molecular Properties

Compound Name1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea
PubChem CID146366370
Molecular FormulaC19H22N4O2S
Molecular Weight370.48 g/mol
Exact Mass370.15
IUPAC Name1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea
SMILESO=C(Nc1csc(-c2ccc(C3=CCOC3)cc2)n1)NC1CCCNC1
InChIInChI=1S/C19H22N4O2S/c24-19(21-16-2-1-8-20-10-16)23-17-12-26-18(22-17)14-5-3-13(4-6-14)15-7-9-25-11-15/h3-7,12,16,20H,1-2,8-11H2,(H2,21,23,24)
InChIKeyGTBVJFIGZJFBSY-UHFFFAOYSA-N
XLogP3.10
TPSA75.28 Ų
H-Bond Donors3
H-Bond Acceptors5
Rotatable Bonds4
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500370.48
LogP ≤ 53.10
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 105

Analyze 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-[2-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl]-3-[(3S)-piperidin-3-yl]urea
CID 146347034
1-[2-[4-(3,6-dihydro-2H-pyran-4-yl)-3-methoxyphenyl]-1,3-thiazol-4-yl]-3-[(3S,4R)-4-fluoropiperidin-3-yl]urea
CID 146366174
1-[2-[4-(3,6-dihydro-2H-pyran-4-yl)-3-methoxyphenyl]-1,3-thiazol-4-yl]-3-[(3R,4S)-4-fluoropiperidin-3-yl]urea
CID 146366175
1-[2-[4-(3,6-dihydro-2H-pyran-4-yl)-3-methoxyphenyl]-1,3-thiazol-4-yl]-3-(4-fluoropiperidin-3-yl)urea
CID 153401134
1-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-3-(2-morpholin-4-ylethyl)urea
CID 140122891
1-[2-[3-methyl-4-(oxan-4-yl)phenyl]-1,3-thiazol-4-yl]-3-[(3S)-piperidin-3-yl]urea
CID 146347027
1-[2-[3-Methyl-4-(oxan-4-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea
CID 146347028
(3S)-3-[carbamoyl-[2-[3-chloro-4-(3,6-dihydro-2H-pyran-4-yl)phenyl]-1,3-thiazol-4-yl]amino]piperidine-1-carboxylic acid
CID 146347039
(3S)-3-[[2-[3-chloro-4-(3,6-dihydro-2H-pyran-4-yl)phenyl]-1,3-thiazol-4-yl]carbamoylamino]piperidine-1-carboxylic acid
CID 146347041
1-[2-[4-(3,6-dihydro-2H-pyran-4-yl)-3-methoxyphenyl]-1,3-thiazol-4-yl]-3-[(3S)-piperidin-3-yl]urea
CID 146347052
1-[2-[4-(3,6-dihydro-2H-pyran-4-yl)-3-methoxyphenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea
CID 146347054
1-[2-[3-chloro-4-(3,6-dihydro-2H-pyran-4-yl)phenyl]-1,3-thiazol-4-yl]-3-[(3S)-piperidin-3-yl]urea
CID 146347068

Frequently Asked Questions

What is the IUPAC name of 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea?
The IUPAC name of 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea (CID 146366370) is 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea.
What is the SMILES notation for 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea?
The canonical SMILES for 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea is O=C(Nc1csc(-c2ccc(C3=CCOC3)cc2)n1)NC1CCCNC1.
What is the InChIKey of 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea?
The InChIKey is GTBVJFIGZJFBSY-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H22N4O2S/c24-19(21-16-2-1-8-20-10-16)23-17-12-26-18(22-17)14-5-3-13(4-6-14)15-7-9-25-11-15/h3-7,12,16,20H,1-2,8-11H2,(H2,21,23,24).
What are the key properties of 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea?
1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea has a molecular weight of 370.48 g/mol, XLogP of 3.10, 4 rotatable bonds, 3 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[2-[4-(2,5-dihydrofuran-3-yl)phenyl]-1,3-thiazol-4-yl]-3-piperidin-3-ylurea is sourced from PubChem (CID 146366370), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).