About 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea
1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea (PubChem CID 146591575) has the molecular formula C15H16BrF3N4O
and a molecular weight of 405.22 g/mol. Its IUPAC name is 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea.
Molecular Properties
| Compound Name | 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea |
| PubChem CID | 146591575 |
| Molecular Formula | C15H16BrF3N4O |
| Molecular Weight | 405.22 g/mol |
| Exact Mass | 404.05 |
| IUPAC Name | 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea |
| SMILES | O=C(Nc1c[nH]c2ccc(Br)nc12)NC1CCC(C(F)(F)F)CC1 |
| InChI | InChI=1S/C15H16BrF3N4O/c16-12-6-5-10-13(23-12)11(7-20-10)22-14(24)21-9-3-1-8(2-4-9)15(17,18)19/h5-9,20H,1-4H2,(H2,21,22,24) |
| InChIKey | KBKZVLLYNJOKAT-UHFFFAOYSA-N |
| XLogP | 4.57 |
| TPSA | 69.81 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 24 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 405.22 |
| LogP ≤ 5 | 4.57 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 2 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea?
The IUPAC name of 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea (CID 146591575) is 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea.
What is the SMILES notation for 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea?
The canonical SMILES for 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea is O=C(Nc1c[nH]c2ccc(Br)nc12)NC1CCC(C(F)(F)F)CC1.
What is the InChIKey of 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea?
The InChIKey is KBKZVLLYNJOKAT-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H16BrF3N4O/c16-12-6-5-10-13(23-12)11(7-20-10)22-14(24)21-9-3-1-8(2-4-9)15(17,18)19/h5-9,20H,1-4H2,(H2,21,22,24).
What are the key properties of 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea?
1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea has a molecular weight of 405.22 g/mol, XLogP of 4.57, 2 rotatable bonds, 3 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(5-bromo-1H-pyrrolo[3,2-b]pyridin-3-yl)-3-[4-(trifluoromethyl)cyclohexyl]urea is sourced from PubChem (CID 146591575), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).