About 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine
5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine (PubChem CID 146636427) has the molecular formula C12H11F4N5O
and a molecular weight of 317.25 g/mol. Its IUPAC name is 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine.
Molecular Properties
| Compound Name | 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine |
| PubChem CID | 146636427 |
| Molecular Formula | C12H11F4N5O |
| Molecular Weight | 317.25 g/mol |
| Exact Mass | 317.09 |
| IUPAC Name | 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine |
| SMILES | COc1nc(-c2cnc(N(C)C)nc2)nc(F)c1C(F)(F)F |
| InChI | InChI=1S/C12H11F4N5O/c1-21(2)11-17-4-6(5-18-11)9-19-8(13)7(12(14,15)16)10(20-9)22-3/h4-5H,1-3H3 |
| InChIKey | XWQVWDNUKMHWSR-UHFFFAOYSA-N |
| XLogP | 2.17 |
| TPSA | 64.03 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 22 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 317.25 |
| LogP ≤ 5 | 2.17 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine?
The IUPAC name of 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine (CID 146636427) is 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine.
What is the SMILES notation for 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine?
The canonical SMILES for 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine is COc1nc(-c2cnc(N(C)C)nc2)nc(F)c1C(F)(F)F.
What is the InChIKey of 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine?
The InChIKey is XWQVWDNUKMHWSR-UHFFFAOYSA-N. The full InChI is InChI=1S/C12H11F4N5O/c1-21(2)11-17-4-6(5-18-11)9-19-8(13)7(12(14,15)16)10(20-9)22-3/h4-5H,1-3H3.
What are the key properties of 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine?
5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine has a molecular weight of 317.25 g/mol, XLogP of 2.17, 3 rotatable bonds, 0 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-N,N-dimethylpyrimidin-2-amine is sourced from PubChem (CID 146636427), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).