5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide

C26H26N10O — CID 146689347

About 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide

5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide (PubChem CID 146689347) has the molecular formula C26H26N10O and a molecular weight of 494.56 g/mol. Its IUPAC name is 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide
• PubChem CID: 146689347
• Molecular Formula: C26H26N10O
• Molecular Weight: 494.56 g/mol
• Exact Mass: 494.23
• IUPAC Name: 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide
• SMILES: Cc1cnn(-c2cnc([C@H](C)NC(=O)c3ccc(-c4nc(C)cc(Cc5cc(C)[nH]n5)n4)cn3)cn2)c1
• InChI: InChI=1S/C26H26N10O/c1-15-10-30-36(14-15)24-13-28-23(12-29-24)18(4)32-26(37)22-6-5-19(11-27-22)25-31-16(2)7-20(33-25)9-21-8-17(3)34-35-21/h5-8,10-14,18H,9H2,1-4H3,(H,32,37)(H,34,35)/t18-/m0/s1
• InChIKey: QFALABLUJHKOJA-SFHVURJKSA-N
• XLogP: 3.24
• TPSA: 140.05 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 9
• Rotatable Bonds: 7
• Heavy Atoms: 37
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	494.56
LogP ≤ 5	3.24
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	9

Frequently Asked Questions

What is the IUPAC name of 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide?

The IUPAC name of 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide (CID 146689347) is 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide.

What is the SMILES notation for 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide?

The canonical SMILES for 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide is Cc1cnn(-c2cnc([C@H](C)NC(=O)c3ccc(-c4nc(C)cc(Cc5cc(C)[nH]n5)n4)cn3)cn2)c1.

What is the InChIKey of 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide?

The InChIKey is QFALABLUJHKOJA-SFHVURJKSA-N. The full InChI is InChI=1S/C26H26N10O/c1-15-10-30-36(14-15)24-13-28-23(12-29-24)18(4)32-26(37)22-6-5-19(11-27-22)25-31-16(2)7-20(33-25)9-21-8-17(3)34-35-21/h5-8,10-14,18H,9H2,1-4H3,(H,32,37)(H,34,35)/t18-/m0/s1.

What are the key properties of 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide?

5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide has a molecular weight of 494.56 g/mol, XLogP of 3.24, 7 rotatable bonds, 2 hydrogen bond donors, and 9 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(1S)-1-[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]ethyl]pyridine-2-carboxamide is sourced from PubChem (CID 146689347), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).