About 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one
3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one (PubChem CID 1472000) has the molecular formula C14H17ClF3N3O
and a molecular weight of 335.76 g/mol. Its IUPAC name is 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one.
Molecular Properties
| Compound Name | 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one |
| PubChem CID | 1472000 |
| Molecular Formula | C14H17ClF3N3O |
| Molecular Weight | 335.76 g/mol |
| Exact Mass | 335.10 |
| IUPAC Name | 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one |
| SMILES | CN1CCN(C(=O)CCc2ncc(C(F)(F)F)cc2Cl)CC1 |
| InChI | InChI=1S/C14H17ClF3N3O/c1-20-4-6-21(7-5-20)13(22)3-2-12-11(15)8-10(9-19-12)14(16,17)18/h8-9H,2-7H2,1H3 |
| InChIKey | QGDGXAUSXZXFKW-UHFFFAOYSA-N |
| XLogP | 2.46 |
| TPSA | 36.44 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 22 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 335.76 |
| LogP ≤ 5 | 2.46 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 3 |
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Frequently Asked Questions
What is the IUPAC name of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one?
The IUPAC name of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one (CID 1472000) is 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one.
What is the SMILES notation for 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one?
The canonical SMILES for 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one is CN1CCN(C(=O)CCc2ncc(C(F)(F)F)cc2Cl)CC1.
What is the InChIKey of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one?
The InChIKey is QGDGXAUSXZXFKW-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H17ClF3N3O/c1-20-4-6-21(7-5-20)13(22)3-2-12-11(15)8-10(9-19-12)14(16,17)18/h8-9H,2-7H2,1H3.
What are the key properties of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one?
3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one has a molecular weight of 335.76 g/mol, XLogP of 2.46, 3 rotatable bonds, 0 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-(4-methylpiperazin-1-yl)propan-1-one is sourced from PubChem (CID 1472000), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).