About 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine
1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine (PubChem CID 149278955) has the molecular formula C30H30N8O2
and a molecular weight of 534.62 g/mol. Its IUPAC name is 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine.
Molecular Properties
| Compound Name | 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine |
| PubChem CID | 149278955 |
| Molecular Formula | C30H30N8O2 |
| Molecular Weight | 534.62 g/mol |
| Exact Mass | 534.25 |
| IUPAC Name | 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine |
| SMILES | C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCC/N=C(\NC#N)Nc4ccncc4)cc23)c1 |
| InChI | InChI=1S/C30H30N8O2/c1-3-22-9-8-10-24(17-22)37-29-25-18-28(27(39-2)19-26(25)35-21-36-29)40-16-7-5-4-6-13-33-30(34-20-31)38-23-11-14-32-15-12-23/h1,8-12,14-15,17-19,21H,4-7,13,16H2,2H3,(H,35,36,37)(H2,32,33,34,38) |
| InChIKey | XSONJYMNNFECBU-UHFFFAOYSA-N |
| XLogP | 5.24 |
| TPSA | 129.37 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 12 |
| Heavy Atoms | 40 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 534.62 |
| LogP ≤ 5 | 5.24 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 8 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'cyanate_/aminonitrile_/thiocyanate', 'substructure': 'N/A'}, {'alert_name': 'enamine', 'substructure': 'N/A'}, {'alert_name': 'imine_1', 'substructure': 'N/A'}, {'alert_name': 'imine_2', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine?
The IUPAC name of 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine (CID 149278955) is 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine.
What is the SMILES notation for 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine?
The canonical SMILES for 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine is C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCC/N=C(\NC#N)Nc4ccncc4)cc23)c1.
What is the InChIKey of 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine?
The InChIKey is XSONJYMNNFECBU-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H30N8O2/c1-3-22-9-8-10-24(17-22)37-29-25-18-28(27(39-2)19-26(25)35-21-36-29)40-16-7-5-4-6-13-33-30(34-20-31)38-23-11-14-32-15-12-23/h1,8-12,14-15,17-19,21H,4-7,13,16H2,2H3,(H,35,36,37)(H2,32,33,34,38).
What are the key properties of 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine?
1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine has a molecular weight of 534.62 g/mol, XLogP of 5.24, 12 rotatable bonds, 3 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 1-cyano-2-[6-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxyhexyl]-3-pyridin-4-ylguanidine is sourced from PubChem (CID 149278955), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).