About ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate
ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate (PubChem CID 15101088) has the molecular formula C18H15ClF3N3O3
and a molecular weight of 413.78 g/mol. Its IUPAC name is ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate.
Molecular Properties
| Compound Name | ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate |
| PubChem CID | 15101088 |
| Molecular Formula | C18H15ClF3N3O3 |
| Molecular Weight | 413.78 g/mol |
| Exact Mass | 413.08 |
| IUPAC Name | ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate |
| SMILES | CCOC(=O)c1cnn2c1N(C(=O)CCl)CC=C2c1cccc(C(F)(F)F)c1 |
| InChI | InChI=1S/C18H15ClF3N3O3/c1-2-28-17(27)13-10-23-25-14(6-7-24(16(13)25)15(26)9-19)11-4-3-5-12(8-11)18(20,21)22/h3-6,8,10H,2,7,9H2,1H3 |
| InChIKey | LAAYLHBSMQSQRU-UHFFFAOYSA-N |
| XLogP | 3.55 |
| TPSA | 64.43 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 413.78 |
| LogP ≤ 5 | 3.55 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'alkyl_halide', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate?
The IUPAC name of ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate (CID 15101088) is ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate.
What is the SMILES notation for ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate?
The canonical SMILES for ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate is CCOC(=O)c1cnn2c1N(C(=O)CCl)CC=C2c1cccc(C(F)(F)F)c1.
What is the InChIKey of ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate?
The InChIKey is LAAYLHBSMQSQRU-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H15ClF3N3O3/c1-2-28-17(27)13-10-23-25-14(6-7-24(16(13)25)15(26)9-19)11-4-3-5-12(8-11)18(20,21)22/h3-6,8,10H,2,7,9H2,1H3.
What are the key properties of ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate?
ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate has a molecular weight of 413.78 g/mol, XLogP of 3.55, 4 rotatable bonds, 0 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for ethyl 4-(2-chloroacetyl)-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carboxylate is sourced from PubChem (CID 15101088), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).