N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide

C22H20F3N5O2 — CID 151283726

IUPACN-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide
SMILESO=C(N[C@H]1COc2ccccc2C1)c1cn2c(n1)CNC(c1cccc(C(F)(F)F)n1)C2
InChIInChI=1S/C22H20F3N5O2/c23-22(24,25)19-7-3-5-15(28-19)16-10-30-11-17(29-20(30)9-26-16)21(31)27-14-8-13-4-1-2-6-18(13)32-12-14/h1-7,11,14,16,26H,8-10,12H2,(H,27,31)/t14-,16?/m1/s1
InChIKeyNYYBSBYEJUDFQA-IURRXHLWSA-N
MW443.43 g/mol
LogP2.87
Rot. Bonds3

About N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide

N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide (PubChem CID 151283726) has the molecular formula C22H20F3N5O2 and a molecular weight of 443.43 g/mol. Its IUPAC name is N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide.

Molecular Properties

Compound NameN-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide
PubChem CID151283726
Molecular FormulaC22H20F3N5O2
Molecular Weight443.43 g/mol
Exact Mass443.16
IUPAC NameN-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide
SMILESO=C(N[C@H]1COc2ccccc2C1)c1cn2c(n1)CNC(c1cccc(C(F)(F)F)n1)C2
InChIInChI=1S/C22H20F3N5O2/c23-22(24,25)19-7-3-5-15(28-19)16-10-30-11-17(29-20(30)9-26-16)21(31)27-14-8-13-4-1-2-6-18(13)32-12-14/h1-7,11,14,16,26H,8-10,12H2,(H,27,31)/t14-,16?/m1/s1
InChIKeyNYYBSBYEJUDFQA-IURRXHLWSA-N
XLogP2.87
TPSA81.07 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds3
Heavy Atoms32
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500443.43
LogP ≤ 52.87
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

Analyze N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide with MolForge

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Related Compounds

N-[2-(4-methoxyphenyl)ethyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 675270
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CID 90286489
5-N-[(7R)-2-[2-(difluoromethoxy)phenyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-4-N,4-N,1-trimethylpyrazole-4,5-dicarboxamide
CID 165414976
PF-03716556
CID 25134521
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
CID 11675867
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-imidazo[1,5-a]pyridin-8-ylmethanone
CID 134144954
9-[(4R)-8-fluoro-3,4-dihydro-2H-chromen-4-yl]-2-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-7H-purin-8-one
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2-ethyl-N-[[4-[[4-(trifluoromethoxy)phenyl]methoxy]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide
CID 70984069
2-ethyl-6-fluoro-N-[[4-[[4-(trifluoromethoxy)phenyl]methoxy]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide
CID 71009858
3-(4-fluorophenyl)-6-[(3-pyridin-4-yloxyazetidin-1-yl)methyl]-7H-imidazo[1,5-a]pyrazin-8-one
CID 71550147
2,7-dimethyl-N-[4-[4-(trifluoromethyl)phenoxy]phenyl]imidazo[1,2-a]pyridine-3-carboxamide
CID 71761816
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-imidazo[4,5-c]pyridin-4-yl)methanone
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Frequently Asked Questions

What is the IUPAC name of N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide?
The IUPAC name of N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide (CID 151283726) is N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide.
What is the SMILES notation for N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide?
The canonical SMILES for N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide is O=C(N[C@H]1COc2ccccc2C1)c1cn2c(n1)CNC(c1cccc(C(F)(F)F)n1)C2.
What is the InChIKey of N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide?
The InChIKey is NYYBSBYEJUDFQA-IURRXHLWSA-N. The full InChI is InChI=1S/C22H20F3N5O2/c23-22(24,25)19-7-3-5-15(28-19)16-10-30-11-17(29-20(30)9-26-16)21(31)27-14-8-13-4-1-2-6-18(13)32-12-14/h1-7,11,14,16,26H,8-10,12H2,(H,27,31)/t14-,16?/m1/s1.
What are the key properties of N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide?
N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide has a molecular weight of 443.43 g/mol, XLogP of 2.87, 3 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(3R)-3,4-dihydro-2H-chromen-3-yl]-6-[6-(trifluoromethyl)-2-pyridinyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxamide is sourced from PubChem (CID 151283726), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).