About ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate
ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate (PubChem CID 151927308) has the molecular formula C20H31F3N2O4Si
and a molecular weight of 448.56 g/mol. Its IUPAC name is ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate.
Molecular Properties
| Compound Name | ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate |
| PubChem CID | 151927308 |
| Molecular Formula | C20H31F3N2O4Si |
| Molecular Weight | 448.56 g/mol |
| Exact Mass | 448.20 |
| IUPAC Name | ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate |
| SMILES | CCOC(=O)CC(=O)c1cnn(C2CC(C)(O[Si](C)(C)C(C)(C)C)C2)c1C(F)(F)F |
| InChI | InChI=1S/C20H31F3N2O4Si/c1-8-28-16(27)9-15(26)14-12-24-25(17(14)20(21,22)23)13-10-19(5,11-13)29-30(6,7)18(2,3)4/h12-13H,8-11H2,1-7H3 |
| InChIKey | SYAPREUQVOLNAT-UHFFFAOYSA-N |
| XLogP | 5.15 |
| TPSA | 70.42 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 448.56 |
| LogP ≤ 5 | 5.15 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 6 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'beta-keto/anhydride', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate?
The IUPAC name of ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate (CID 151927308) is ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate.
What is the SMILES notation for ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate?
The canonical SMILES for ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate is CCOC(=O)CC(=O)c1cnn(C2CC(C)(O[Si](C)(C)C(C)(C)C)C2)c1C(F)(F)F.
What is the InChIKey of ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate?
The InChIKey is SYAPREUQVOLNAT-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H31F3N2O4Si/c1-8-28-16(27)9-15(26)14-12-24-25(17(14)20(21,22)23)13-10-19(5,11-13)29-30(6,7)18(2,3)4/h12-13H,8-11H2,1-7H3.
What are the key properties of ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate?
ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate has a molecular weight of 448.56 g/mol, XLogP of 5.15, 7 rotatable bonds, 0 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for ethyl 3-[1-[3-[tert-butyl(dimethyl)silyl]oxy-3-methylcyclobutyl]-5-(trifluoromethyl)pyrazol-4-yl]-3-oxopropanoate is sourced from PubChem (CID 151927308), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).