2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole

C11H8F2N4S — CID 153418445

IUPAC2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole
SMILESCc1ccnc(-c2cnc3sc(C(F)F)cn23)n1
InChIInChI=1S/C11H8F2N4S/c1-6-2-3-14-10(16-6)7-4-15-11-17(7)5-8(18-11)9(12)13/h2-5,9H,1H3
InChIKeyMFWAGZFFVAROLN-UHFFFAOYSA-N
MW266.28 g/mol
LogP3.10
Rot. Bonds2

About 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole

2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole (PubChem CID 153418445) has the molecular formula C11H8F2N4S and a molecular weight of 266.28 g/mol. Its IUPAC name is 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole.

Molecular Properties

Compound Name2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole
PubChem CID153418445
Molecular FormulaC11H8F2N4S
Molecular Weight266.28 g/mol
Exact Mass266.04
IUPAC Name2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole
SMILESCc1ccnc(-c2cnc3sc(C(F)F)cn23)n1
InChIInChI=1S/C11H8F2N4S/c1-6-2-3-14-10(16-6)7-4-15-11-17(7)5-8(18-11)9(12)13/h2-5,9H,1H3
InChIKeyMFWAGZFFVAROLN-UHFFFAOYSA-N
XLogP3.10
TPSA43.08 Ų
H-Bond Donors
H-Bond Acceptors5
Rotatable Bonds2
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500266.28
LogP ≤ 53.10
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 105

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Related Compounds

4-[(E)-2-(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)ethenyl]pyrimidin-2-amine
CID 44587324
4-methyl-N-[(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]pyrimidin-2-amine
CID 72890425
6-{[(4,6-Dimethylpyrimidin-2-yl)sulfanyl]methyl}-3-methylimidazo[2,1-b][1,3]thiazole
CID 700769
6-(Pyrimidin-2-ylsulfanylmethyl)imidazo[2,1-b][1,3]thiazole
CID 4447936
2-ethyl-4-{1-[(2-methyl-1,3-thiazol-4-yl)methyl]-1H-imidazol-2-yl}pyrimidine
CID 56872847
N,N-dimethyl-2-[4-(5-methyl-1,3-thiazol-2-yl)piperazin-1-yl]-6-(trifluoromethyl)pyrimidin-4-amine
CID 72104989
3-(Thiazol-2-yl)-7-trifluoromethyl-imidazo[1,2-alpha]pyrimidine
CID 9835150
6-(5-Methyl-1,3-thiazol-2-yl)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrimidin-4-amine
CID 70843532
6-(1-Methylimidazol-2-yl)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrimidin-4-amine
CID 70843562
2-[4-(1,3-Thiazol-2-yl)pyrimidin-2-yl]-4-(trifluoromethyl)-1,3-thiazole
CID 90880835
2-[4-(1-Methylimidazol-2-yl)pyrimidin-2-yl]-4-(trifluoromethyl)-1,3-thiazole
CID 90885050
2-[4-(4-Methyl-1,3-thiazol-2-yl)pyrimidin-2-yl]-4-(trifluoromethyl)-1,3-thiazole
CID 91001661

Frequently Asked Questions

What is the IUPAC name of 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole?
The IUPAC name of 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole (CID 153418445) is 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole.
What is the SMILES notation for 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole?
The canonical SMILES for 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole is Cc1ccnc(-c2cnc3sc(C(F)F)cn23)n1.
What is the InChIKey of 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole?
The InChIKey is MFWAGZFFVAROLN-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H8F2N4S/c1-6-2-3-14-10(16-6)7-4-15-11-17(7)5-8(18-11)9(12)13/h2-5,9H,1H3.
What are the key properties of 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole?
2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole has a molecular weight of 266.28 g/mol, XLogP of 3.10, 2 rotatable bonds, 0 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(difluoromethyl)-5-(4-methylpyrimidin-2-yl)imidazo[2,1-b][1,3]thiazole is sourced from PubChem (CID 153418445), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).