About 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile
3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile (PubChem CID 154571771) has the molecular formula C20H25FN2O3
and a molecular weight of 360.43 g/mol. Its IUPAC name is 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile.
Molecular Properties
| Compound Name | 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile |
| PubChem CID | 154571771 |
| Molecular Formula | C20H25FN2O3 |
| Molecular Weight | 360.43 g/mol |
| Exact Mass | 360.18 |
| IUPAC Name | 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile |
| SMILES | CC(C)[C@H]1C[C@@H](O)CC2(CCN(C(=O)c3ccc(C#N)cc3F)CC2)O1 |
| InChI | InChI=1S/C20H25FN2O3/c1-13(2)18-10-15(24)11-20(26-18)5-7-23(8-6-20)19(25)16-4-3-14(12-22)9-17(16)21/h3-4,9,13,15,18,24H,5-8,10-11H2,1-2H3/t15-,18-/m1/s1 |
| InChIKey | FGWUNTHKJCVUPD-CRAIPNDOSA-N |
| XLogP | 2.87 |
| TPSA | 73.56 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 26 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 360.43 |
| LogP ≤ 5 | 2.87 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile?
The IUPAC name of 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile (CID 154571771) is 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile.
What is the SMILES notation for 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile?
The canonical SMILES for 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile is CC(C)[C@H]1C[C@@H](O)CC2(CCN(C(=O)c3ccc(C#N)cc3F)CC2)O1.
What is the InChIKey of 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile?
The InChIKey is FGWUNTHKJCVUPD-CRAIPNDOSA-N. The full InChI is InChI=1S/C20H25FN2O3/c1-13(2)18-10-15(24)11-20(26-18)5-7-23(8-6-20)19(25)16-4-3-14(12-22)9-17(16)21/h3-4,9,13,15,18,24H,5-8,10-11H2,1-2H3/t15-,18-/m1/s1.
What are the key properties of 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile?
3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile has a molecular weight of 360.43 g/mol, XLogP of 2.87, 2 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 3-fluoro-4-[(2R,4R)-4-hydroxy-2-propan-2-yl-1-oxa-9-azaspiro[5.5]undecane-9-carbonyl]benzonitrile is sourced from PubChem (CID 154571771), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).