About (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone
(2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone (PubChem CID 154749074) has the molecular formula C13H14F3N3O2
and a molecular weight of 301.27 g/mol. Its IUPAC name is (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone.
Molecular Properties
| Compound Name | (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone |
| PubChem CID | 154749074 |
| Molecular Formula | C13H14F3N3O2 |
| Molecular Weight | 301.27 g/mol |
| Exact Mass | 301.10 |
| IUPAC Name | (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone |
| SMILES | O=C(c1ccnc(C2CC2)n1)N1CCC(O)(C(F)(F)F)C1 |
| InChI | InChI=1S/C13H14F3N3O2/c14-13(15,16)12(21)4-6-19(7-12)11(20)9-3-5-17-10(18-9)8-1-2-8/h3,5,8,21H,1-2,4,6-7H2 |
| InChIKey | JBLBNFCSSBGWRG-UHFFFAOYSA-N |
| XLogP | 1.49 |
| TPSA | 66.32 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 21 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 301.27 |
| LogP ≤ 5 | 1.49 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone?
The IUPAC name of (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone (CID 154749074) is (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone.
What is the SMILES notation for (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone?
The canonical SMILES for (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone is O=C(c1ccnc(C2CC2)n1)N1CCC(O)(C(F)(F)F)C1.
What is the InChIKey of (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone?
The InChIKey is JBLBNFCSSBGWRG-UHFFFAOYSA-N. The full InChI is InChI=1S/C13H14F3N3O2/c14-13(15,16)12(21)4-6-19(7-12)11(20)9-3-5-17-10(18-9)8-1-2-8/h3,5,8,21H,1-2,4,6-7H2.
What are the key properties of (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone?
(2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone has a molecular weight of 301.27 g/mol, XLogP of 1.49, 2 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (2-cyclopropylpyrimidin-4-yl)-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]methanone is sourced from PubChem (CID 154749074), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).