3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione

C49H62FN9O4 — CID 155166735

IUPAC3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
SMILESC[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC4(CCN(CCC5CCN(c6ccc7c(c6)CN(C6CCC(=O)NC6=O)C7=O)CC5)CCO4)CC3)nc2)N1CC(C)(C)F
InChIInChI=1S/C49H62FN9O4/c1-32-26-39-38-6-4-5-7-40(38)53-43(39)44(59(32)31-48(2,3)50)35-28-51-47(52-29-35)57-22-16-49(17-23-57)15-21-55(24-25-63-49)18-12-33-13-19-56(20-14-33)36-8-9-37-34(27-36)30-58(46(37)62)41-10-11-42(60)54-45(41)61/h4-9,27-29,32-33,41,44,53H,10-26,30-31H2,1-3H3,(H,54,60,61)/t32-,41?,44-/m1/s1
InChIKeyFIXYMPMIWAAQGU-GNDFOHGCSA-N
MW860.09 g/mol
LogP6.17
Rot. Bonds9

About 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione

3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione (PubChem CID 155166735) has the molecular formula C49H62FN9O4 and a molecular weight of 860.09 g/mol. Its IUPAC name is 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione.

Molecular Properties

Compound Name3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
PubChem CID155166735
Molecular FormulaC49H62FN9O4
Molecular Weight860.09 g/mol
Exact Mass859.49
IUPAC Name3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
SMILESC[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC4(CCN(CCC5CCN(c6ccc7c(c6)CN(C6CCC(=O)NC6=O)C7=O)CC5)CCO4)CC3)nc2)N1CC(C)(C)F
InChIInChI=1S/C49H62FN9O4/c1-32-26-39-38-6-4-5-7-40(38)53-43(39)44(59(32)31-48(2,3)50)35-28-51-47(52-29-35)57-22-16-49(17-23-57)15-21-55(24-25-63-49)18-12-33-13-19-56(20-14-33)36-8-9-37-34(27-36)30-58(46(37)62)41-10-11-42(60)54-45(41)61/h4-9,27-29,32-33,41,44,53H,10-26,30-31H2,1-3H3,(H,54,60,61)/t32-,41?,44-/m1/s1
InChIKeyFIXYMPMIWAAQGU-GNDFOHGCSA-N
XLogP6.17
TPSA130.24 Ų
H-Bond Donors2
H-Bond Acceptors10
Rotatable Bonds9
Heavy Atoms63
Complexity—

Lipinski Rule of Five

2 violations

RuleValue
MW ≤ 500860.09
LogP ≤ 56.17
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 1010

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'indol_3yl_alk(461)', 'substructure': 'N/A'}, {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Analyze 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione with MolForge

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Frequently Asked Questions

What is the IUPAC name of 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione?
The IUPAC name of 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione (CID 155166735) is 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione.
What is the SMILES notation for 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione?
The canonical SMILES for 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione is C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC4(CCN(CCC5CCN(c6ccc7c(c6)CN(C6CCC(=O)NC6=O)C7=O)CC5)CCO4)CC3)nc2)N1CC(C)(C)F.
What is the InChIKey of 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione?
The InChIKey is FIXYMPMIWAAQGU-GNDFOHGCSA-N. The full InChI is InChI=1S/C49H62FN9O4/c1-32-26-39-38-6-4-5-7-40(38)53-43(39)44(59(32)31-48(2,3)50)35-28-51-47(52-29-35)57-22-16-49(17-23-57)15-21-55(24-25-63-49)18-12-33-13-19-56(20-14-33)36-8-9-37-34(27-36)30-58(46(37)62)41-10-11-42(60)54-45(41)61/h4-9,27-29,32-33,41,44,53H,10-26,30-31H2,1-3H3,(H,54,60,61)/t32-,41?,44-/m1/s1.
What are the key properties of 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione?
3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione has a molecular weight of 860.09 g/mol, XLogP of 6.17, 9 rotatable bonds, 2 hydrogen bond donors, and 10 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[6-[4-[2-[3-[5-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyrimidin-2-yl]-7-oxa-3,10-diazaspiro[5.6]dodecan-10-yl]ethyl]piperidin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione is sourced from PubChem (CID 155166735), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).