About 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine
5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine (PubChem CID 155176677) has the molecular formula C19H20ClF2N5O
and a molecular weight of 407.85 g/mol. Its IUPAC name is 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine.
Molecular Properties
| Compound Name | 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine |
| PubChem CID | 155176677 |
| Molecular Formula | C19H20ClF2N5O |
| Molecular Weight | 407.85 g/mol |
| Exact Mass | 407.13 |
| IUPAC Name | 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine |
| SMILES | Cc1c(OCCCNc2ncnc(C(F)F)c2Cl)nn(C)c1-c1ccccc1 |
| InChI | InChI=1S/C19H20ClF2N5O/c1-12-16(13-7-4-3-5-8-13)27(2)26-19(12)28-10-6-9-23-18-14(20)15(17(21)22)24-11-25-18/h3-5,7-8,11,17H,6,9-10H2,1-2H3,(H,23,24,25) |
| InChIKey | ZPMXYOOOBGCRQJ-UHFFFAOYSA-N |
| XLogP | 4.66 |
| TPSA | 64.86 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 407.85 |
| LogP ≤ 5 | 4.66 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine?
The IUPAC name of 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine (CID 155176677) is 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine.
What is the SMILES notation for 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine?
The canonical SMILES for 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine is Cc1c(OCCCNc2ncnc(C(F)F)c2Cl)nn(C)c1-c1ccccc1.
What is the InChIKey of 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine?
The InChIKey is ZPMXYOOOBGCRQJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H20ClF2N5O/c1-12-16(13-7-4-3-5-8-13)27(2)26-19(12)28-10-6-9-23-18-14(20)15(17(21)22)24-11-25-18/h3-5,7-8,11,17H,6,9-10H2,1-2H3,(H,23,24,25).
What are the key properties of 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine?
5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine has a molecular weight of 407.85 g/mol, XLogP of 4.66, 8 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-6-(difluoromethyl)-N-[3-(1,4-dimethyl-5-phenylpyrazol-3-yl)oxypropyl]pyrimidin-4-amine is sourced from PubChem (CID 155176677), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).