About [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone
[3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone (PubChem CID 155227736) has the molecular formula C26H26FN5O2
and a molecular weight of 459.53 g/mol. Its IUPAC name is [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone.
Molecular Properties
| Compound Name | [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone |
| PubChem CID | 155227736 |
| Molecular Formula | C26H26FN5O2 |
| Molecular Weight | 459.53 g/mol |
| Exact Mass | 459.21 |
| IUPAC Name | [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone |
| SMILES | COC[C@H]1CCCC1C(=O)c1nc(-c2ccc3ncc(C)n3c2)c(-c2ccc(F)cc2)nc1N |
| InChI | InChI=1S/C26H26FN5O2/c1-15-12-29-21-11-8-17(13-32(15)21)23-22(16-6-9-19(27)10-7-16)31-26(28)24(30-23)25(33)20-5-3-4-18(20)14-34-2/h6-13,18,20H,3-5,14H2,1-2H3,(H2,28,31)/t18-,20?/m1/s1 |
| InChIKey | BJRRHKZGSTYRGS-QSVWIEALSA-N |
| XLogP | 4.73 |
| TPSA | 95.40 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 459.53 |
| LogP ≤ 5 | 4.73 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone?
The IUPAC name of [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone (CID 155227736) is [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone.
What is the SMILES notation for [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone?
The canonical SMILES for [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone is COC[C@H]1CCCC1C(=O)c1nc(-c2ccc3ncc(C)n3c2)c(-c2ccc(F)cc2)nc1N.
What is the InChIKey of [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone?
The InChIKey is BJRRHKZGSTYRGS-QSVWIEALSA-N. The full InChI is InChI=1S/C26H26FN5O2/c1-15-12-29-21-11-8-17(13-32(15)21)23-22(16-6-9-19(27)10-7-16)31-26(28)24(30-23)25(33)20-5-3-4-18(20)14-34-2/h6-13,18,20H,3-5,14H2,1-2H3,(H2,28,31)/t18-,20?/m1/s1.
What are the key properties of [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone?
[3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone has a molecular weight of 459.53 g/mol, XLogP of 4.73, 6 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for [3-amino-5-(4-fluorophenyl)-6-(3-methylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl]-[(2S)-2-(methoxymethyl)cyclopentyl]methanone is sourced from PubChem (CID 155227736), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).