About 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one
3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one (PubChem CID 155270193) has the molecular formula C21H30F2N8O2
and a molecular weight of 464.52 g/mol. Its IUPAC name is 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one.
Molecular Properties
| Compound Name | 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one |
| PubChem CID | 155270193 |
| Molecular Formula | C21H30F2N8O2 |
| Molecular Weight | 464.52 g/mol |
| Exact Mass | 464.25 |
| IUPAC Name | 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one |
| SMILES | CN1CCC(n2cc(Nc3ncc(C(F)F)c(NCCCN4CCCOC4=O)n3)cn2)CC1 |
| InChI | InChI=1S/C21H30F2N8O2/c1-29-9-4-16(5-10-29)31-14-15(12-26-31)27-20-25-13-17(18(22)23)19(28-20)24-6-2-7-30-8-3-11-33-21(30)32/h12-14,16,18H,2-11H2,1H3,(H2,24,25,27,28) |
| InChIKey | YQWFHSNMUWRORK-UHFFFAOYSA-N |
| XLogP | 3.27 |
| TPSA | 100.44 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 9 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 464.52 |
| LogP ≤ 5 | 3.27 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 9 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one?
The IUPAC name of 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one (CID 155270193) is 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one.
What is the SMILES notation for 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one?
The canonical SMILES for 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one is CN1CCC(n2cc(Nc3ncc(C(F)F)c(NCCCN4CCCOC4=O)n3)cn2)CC1.
What is the InChIKey of 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one?
The InChIKey is YQWFHSNMUWRORK-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H30F2N8O2/c1-29-9-4-16(5-10-29)31-14-15(12-26-31)27-20-25-13-17(18(22)23)19(28-20)24-6-2-7-30-8-3-11-33-21(30)32/h12-14,16,18H,2-11H2,1H3,(H2,24,25,27,28).
What are the key properties of 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one?
3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one has a molecular weight of 464.52 g/mol, XLogP of 3.27, 9 rotatable bonds, 2 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[3-[[5-(difluoromethyl)-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]-1,3-oxazinan-2-one is sourced from PubChem (CID 155270193), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).