4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

C24H25N9 — CID 155406025

IUPAC4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCn1ccc(-c2cc(-c3cnc(N4C[C@@H]5CC(C)(N)C[C@@H]5C4)cn3)c3c(C#N)cnn3c2)n1
InChIInChI=1S/C24H25N9/c1-24(26)6-16-12-32(13-17(16)7-24)22-11-27-21(10-28-22)19-5-15(20-3-4-31(2)30-20)14-33-23(19)18(8-25)9-29-33/h3-5,9-11,14,16-17H,6-7,12-13,26H2,1-2H3/t16-,17+,24?
InChIKeyFITONRMBQRNQOK-LDSCYUJKSA-N
MW439.53 g/mol
LogP2.63
Rot. Bonds3

About 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile (PubChem CID 155406025) has the molecular formula C24H25N9 and a molecular weight of 439.53 g/mol. Its IUPAC name is 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile.

Molecular Properties

Compound Name4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
PubChem CID155406025
Molecular FormulaC24H25N9
Molecular Weight439.53 g/mol
Exact Mass439.22
IUPAC Name4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCn1ccc(-c2cc(-c3cnc(N4C[C@@H]5CC(C)(N)C[C@@H]5C4)cn3)c3c(C#N)cnn3c2)n1
InChIInChI=1S/C24H25N9/c1-24(26)6-16-12-32(13-17(16)7-24)22-11-27-21(10-28-22)19-5-15(20-3-4-31(2)30-20)14-33-23(19)18(8-25)9-29-33/h3-5,9-11,14,16-17H,6-7,12-13,26H2,1-2H3/t16-,17+,24?
InChIKeyFITONRMBQRNQOK-LDSCYUJKSA-N
XLogP2.63
TPSA113.95 Ų
H-Bond Donors1
H-Bond Acceptors9
Rotatable Bonds3
Heavy Atoms33
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500439.53
LogP ≤ 52.63
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 109

Analyze 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-[5-[6-(aminomethyl)-3-azabicyclo[3.1.0]hexan-3-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 164818273
N-[(3aS,6aR)-2-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-5-yl]formamide
CID 164818225
4-[5-[(3aR,6aS)-5-(2-chloro-6-fluorophenyl)sulfonyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 155406384
tert-butyl N-[[(1R,5S)-3-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]pyrazin-2-yl]-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate
CID 164818167
6-(1-methylpyrazol-4-yl)-4-[5-(4-prop-2-ynoylpiperazin-1-yl)pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 164754963
4-[6-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;hydrochloride
CID 155388164
tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]pyrazin-2-yl]piperazine-1-carboxylate
CID 140882208
N-[(3aR,6aS)-2-[5-[3-cyano-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridin-4-yl]pyrazin-2-yl]-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-5-yl]-3-chloropyridine-2-carboxamide
CID 155388117
N-[(3aS,6aR)-2-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-5-yl]-6-methoxypyridine-3-carboxamide
CID 155388144
tert-butyl 3-[5-[3-cyano-6-[1-(difluoromethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridin-4-yl]pyrazin-2-yl]-3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
CID 155576270
4-[5-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 174152568
6-(1-methylpyrazol-4-yl)-4-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 126740454

Frequently Asked Questions

What is the IUPAC name of 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The IUPAC name of 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile (CID 155406025) is 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile.
What is the SMILES notation for 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The canonical SMILES for 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile is Cn1ccc(-c2cc(-c3cnc(N4C[C@@H]5CC(C)(N)C[C@@H]5C4)cn3)c3c(C#N)cnn3c2)n1.
What is the InChIKey of 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The InChIKey is FITONRMBQRNQOK-LDSCYUJKSA-N. The full InChI is InChI=1S/C24H25N9/c1-24(26)6-16-12-32(13-17(16)7-24)22-11-27-21(10-28-22)19-5-15(20-3-4-31(2)30-20)14-33-23(19)18(8-25)9-29-33/h3-5,9-11,14,16-17H,6-7,12-13,26H2,1-2H3/t16-,17+,24?.
What are the key properties of 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile has a molecular weight of 439.53 g/mol, XLogP of 2.63, 3 rotatable bonds, 1 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[5-[(3aS,6aR)-5-amino-5-methyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-2-yl]pyrazin-2-yl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile is sourced from PubChem (CID 155406025), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).