About 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide
2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide (PubChem CID 155737882) has the molecular formula C18H14ClF2N3O4
and a molecular weight of 409.78 g/mol. Its IUPAC name is 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide.
Molecular Properties
| Compound Name | 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide |
| PubChem CID | 155737882 |
| Molecular Formula | C18H14ClF2N3O4 |
| Molecular Weight | 409.78 g/mol |
| Exact Mass | 409.06 |
| IUPAC Name | 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide |
| SMILES | Cc1ccc(-c2[nH]nc(-c3ccc(Cl)c(O)c3F)c2CC(=O)NO)c(F)c1O |
| InChI | InChI=1S/C18H14ClF2N3O4/c1-7-2-3-8(13(20)17(7)26)15-10(6-12(25)24-28)16(23-22-15)9-4-5-11(19)18(27)14(9)21/h2-5,26-28H,6H2,1H3,(H,22,23)(H,24,25) |
| InChIKey | UKCNEMTWGBCJGQ-UHFFFAOYSA-N |
| XLogP | 3.44 |
| TPSA | 118.47 Ų |
| H-Bond Donors | 5 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 409.78 |
| LogP ≤ 5 | 3.44 |
| H-Bond Donors ≤ 5 | 5 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide?
The IUPAC name of 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide (CID 155737882) is 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide.
What is the SMILES notation for 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide?
The canonical SMILES for 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide is Cc1ccc(-c2[nH]nc(-c3ccc(Cl)c(O)c3F)c2CC(=O)NO)c(F)c1O.
What is the InChIKey of 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide?
The InChIKey is UKCNEMTWGBCJGQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H14ClF2N3O4/c1-7-2-3-8(13(20)17(7)26)15-10(6-12(25)24-28)16(23-22-15)9-4-5-11(19)18(27)14(9)21/h2-5,26-28H,6H2,1H3,(H,22,23)(H,24,25).
What are the key properties of 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide?
2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide has a molecular weight of 409.78 g/mol, XLogP of 3.44, 4 rotatable bonds, 5 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(4-chloro-2-fluoro-3-hydroxyphenyl)-5-(2-fluoro-3-hydroxy-4-methylphenyl)-1H-pyrazol-4-yl]-N-hydroxyacetamide is sourced from PubChem (CID 155737882), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).