About N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide
N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide (PubChem CID 155778877) has the molecular formula C23H16Cl2FN3O2
and a molecular weight of 456.30 g/mol. Its IUPAC name is N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide.
Molecular Properties
| Compound Name | N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide |
| PubChem CID | 155778877 |
| Molecular Formula | C23H16Cl2FN3O2 |
| Molecular Weight | 456.30 g/mol |
| Exact Mass | 455.06 |
| IUPAC Name | N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide |
| SMILES | Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1ccnc(Cl)c1F |
| InChI | InChI=1S/C23H16Cl2FN3O2/c1-13-16(23(30)29-12-14-7-9-28-22(25)21(14)26)3-2-4-19(13)31-20-8-10-27-18-11-15(24)5-6-17(18)20/h2-11H,12H2,1H3,(H,29,30) |
| InChIKey | YDBAXSCOMKEZSI-UHFFFAOYSA-N |
| XLogP | 6.11 |
| TPSA | 64.11 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 456.30 |
| LogP ≤ 5 | 6.11 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide?
The IUPAC name of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide (CID 155778877) is N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide.
What is the SMILES notation for N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide?
The canonical SMILES for N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide is Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1ccnc(Cl)c1F.
What is the InChIKey of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide?
The InChIKey is YDBAXSCOMKEZSI-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H16Cl2FN3O2/c1-13-16(23(30)29-12-14-7-9-28-22(25)21(14)26)3-2-4-19(13)31-20-8-10-27-18-11-15(24)5-6-17(18)20/h2-11H,12H2,1H3,(H,29,30).
What are the key properties of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide?
N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide has a molecular weight of 456.30 g/mol, XLogP of 6.11, 5 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-chloroquinolin-4-yl)oxy-2-methylbenzamide is sourced from PubChem (CID 155778877), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).