About N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide
N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide (PubChem CID 155779126) has the molecular formula C24H19ClFN3O3
and a molecular weight of 451.89 g/mol. Its IUPAC name is N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide.
Molecular Properties
| Compound Name | N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide |
| PubChem CID | 155779126 |
| Molecular Formula | C24H19ClFN3O3 |
| Molecular Weight | 451.89 g/mol |
| Exact Mass | 451.11 |
| IUPAC Name | N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide |
| SMILES | COc1ccc2c(Oc3cccc(C(=O)NCc4ccnc(Cl)c4F)c3C)ccnc2c1 |
| InChI | InChI=1S/C24H19ClFN3O3/c1-14-17(24(30)29-13-15-8-10-28-23(25)22(15)26)4-3-5-20(14)32-21-9-11-27-19-12-16(31-2)6-7-18(19)21/h3-12H,13H2,1-2H3,(H,29,30) |
| InChIKey | LIYIBDWTBHYDBJ-UHFFFAOYSA-N |
| XLogP | 5.46 |
| TPSA | 73.34 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 451.89 |
| LogP ≤ 5 | 5.46 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide?
The IUPAC name of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide (CID 155779126) is N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide.
What is the SMILES notation for N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide?
The canonical SMILES for N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide is COc1ccc2c(Oc3cccc(C(=O)NCc4ccnc(Cl)c4F)c3C)ccnc2c1.
What is the InChIKey of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide?
The InChIKey is LIYIBDWTBHYDBJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H19ClFN3O3/c1-14-17(24(30)29-13-15-8-10-28-23(25)22(15)26)4-3-5-20(14)32-21-9-11-27-19-12-16(31-2)6-7-18(19)21/h3-12H,13H2,1-2H3,(H,29,30).
What are the key properties of N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide?
N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide has a molecular weight of 451.89 g/mol, XLogP of 5.46, 6 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(2-chloro-3-fluoro-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide is sourced from PubChem (CID 155779126), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).