4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide

C₁₇H₂₀FN₇OS — CID 156888612

About 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide

4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide (PubChem CID 156888612) has the molecular formula C₁₇H₂₀FN₇OS and a molecular weight of 389.46 g/mol. Its IUPAC name is 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide.

Molecular Properties

• Compound Name: 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide
• PubChem CID: 156888612
• Molecular Formula: C₁₇H₂₀FN₇OS
• Molecular Weight: 389.46 g/mol
• Exact Mass: 389.14
• IUPAC Name: 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide
• SMILES: Cc1cn2cc(NC(=O)c3sc(N4CCN(C)CC4)nc3N)cc(F)c2n1
• InChI: InChI=1S/C17H20FN7OS/c1-10-8-25-9-11(7-12(18)15(25)20-10)21-16(26)13-14(19)22-17(27-13)24-5-3-23(2)4-6-24/h7-9H,3-6,19H2,1-2H3,(H,21,26)
• InChIKey: LBACQRGKWZXFTF-UHFFFAOYSA-N
• XLogP: 1.82
• TPSA: 91.79 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 8
• Rotatable Bonds: 3
• Heavy Atoms: 27
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	389.46
LogP ≤ 5	1.82
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	8

Frequently Asked Questions

What is the IUPAC name of 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide?

The IUPAC name of 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide (CID 156888612) is 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide.

What is the SMILES notation for 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide?

The canonical SMILES for 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide is Cc1cn2cc(NC(=O)c3sc(N4CCN(C)CC4)nc3N)cc(F)c2n1.

What is the InChIKey of 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide?

The InChIKey is LBACQRGKWZXFTF-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H20FN7OS/c1-10-8-25-9-11(7-12(18)15(25)20-10)21-16(26)13-14(19)22-17(27-13)24-5-3-23(2)4-6-24/h7-9H,3-6,19H2,1-2H3,(H,21,26).

What are the key properties of 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide?

4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide has a molecular weight of 389.46 g/mol, XLogP of 1.82, 3 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.

Where does this data come from?

All data for 4-amino-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide is sourced from PubChem (CID 156888612), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 156888612 — identifiers, structure, computed properties (public domain)

How this page is built: methodology · editorial policy & corrections.