N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane

C127H163F6N11O13 — CID 157065444

About N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane

N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane (PubChem CID 157065444) has the molecular formula C127H163F6N11O13 and a molecular weight of 2165.75 g/mol. Its IUPAC name is N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane.

Molecular Properties

• Compound Name: N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane
• PubChem CID: 157065444
• Molecular Formula: C127H163F6N11O13
• Molecular Weight: 2165.75 g/mol
• Exact Mass: 2164.23
• IUPAC Name: N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane
• SMILES: C.C.C.C.C.CCN(CC)C(=O)c1ccc(C2=CC3(CCNCC3)Cc3ccc(F)cc32)c(O)c1.CCN(CC)C(=O)c1ccc(C2=CC3(CCNCC3)Oc3ccc(F)cc32)c(O)c1.CCN(CC)C(=O)c1ccc(C2=CC3(CCNCC3)Oc3cccc(OC(F)F)c32)cn1.CCN(CC)C(=O)c1ccc(C2CC3(CCNCC3)Cc3ccc(F)cc32)c(O)c1.CCN(CC)C(=O)c1ccc(C2CC3(CCNCC3)Oc3ccc(F)cc32)c(O)c1
• InChI: InChI=1S/C25H31FN2O2.C25H29FN2O2.C24H27F2N3O3.C24H29FN2O3.C24H27FN2O3.5CH4/c2*1-3-28(4-2)24(30)17-6-8-20(23(29)13-17)22-16-25(9-11-27-12-10-25)15-18-5-7-19(26)14-21(18)22;1-3-29(4-2)22(30)18-9-8-16(15-28-18)17-14-24(10-12-27-13-11-24)32-20-7-5-6-19(21(17)20)31-23(25)26;2*1-3-27(4-2)23(29)16-5-7-18(21(28)13-16)20-15-24(9-11-26-12-10-24)30-22-8-6-17(25)14-19(20)22;;;;;/h5-8,13-14,22,27,29H,3-4,9-12,15-16H2,1-2H3;5-8,13-14,16,27,29H,3-4,9-12,15H2,1-2H3;5-9,14-15,23,27H,3-4,10-13H2,1-2H3;5-8,13-14,20,26,28H,3-4,9-12,15H2,1-2H3;5-8,13-15,26,28H,3-4,9-12H2,1-2H3;5*1H4
• InChIKey: ABVBLPNFSSOFCZ-UHFFFAOYSA-N
• XLogP: 24.13
• TPSA: 292.43 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 19
• Rotatable Bonds: 22
• Heavy Atoms: 157
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2165.75
LogP ≤ 5	24.13
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	19

Frequently Asked Questions

What is the IUPAC name of N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane?

The IUPAC name of N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane (CID 157065444) is N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane.

What is the SMILES notation for N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane?

The canonical SMILES for N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane is C.C.C.C.C.CCN(CC)C(=O)c1ccc(C2=CC3(CCNCC3)Cc3ccc(F)cc32)c(O)c1.CCN(CC)C(=O)c1ccc(C2=CC3(CCNCC3)Oc3ccc(F)cc32)c(O)c1.CCN(CC)C(=O)c1ccc(C2=CC3(CCNCC3)Oc3cccc(OC(F)F)c32)cn1.CCN(CC)C(=O)c1ccc(C2CC3(CCNCC3)Cc3ccc(F)cc32)c(O)c1.CCN(CC)C(=O)c1ccc(C2CC3(CCNCC3)Oc3ccc(F)cc32)c(O)c1.

What is the InChIKey of N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane?

The InChIKey is ABVBLPNFSSOFCZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H31FN2O2.C25H29FN2O2.C24H27F2N3O3.C24H29FN2O3.C24H27FN2O3.5CH4/c2*1-3-28(4-2)24(30)17-6-8-20(23(29)13-17)22-16-25(9-11-27-12-10-25)15-18-5-7-19(26)14-21(18)22;1-3-29(4-2)22(30)18-9-8-16(15-28-18)17-14-24(10-12-27-13-11-24)32-20-7-5-6-19(21(17)20)31-23(25)26;2*1-3-27(4-2)23(29)16-5-7-18(21(28)13-16)20-15-24(9-11-26-12-10-24)30-22-8-6-17(25)14-19(20)22;;;;;/h5-8,13-14,22,27,29H,3-4,9-12,15-16H2,1-2H3;5-8,13-14,16,27,29H,3-4,9-12,15H2,1-2H3;5-9,14-15,23,27H,3-4,10-13H2,1-2H3;5-8,13-14,20,26,28H,3-4,9-12,15H2,1-2H3;5-8,13-15,26,28H,3-4,9-12H2,1-2H3;5*1H4.

What are the key properties of N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane?

N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane has a molecular weight of 2165.75 g/mol, XLogP of 24.13, 22 rotatable bonds, 9 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for N,N-diethyl-4-(6-fluorospiro[chromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-4-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[2,4-dihydro-1H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;N,N-diethyl-4-(7-fluorospiro[4H-naphthalene-3,4'-piperidine]-1-yl)-3-hydroxybenzamide;5-[5-(difluoromethoxy)spiro[chromene-2,4'-piperidine]-4-yl]-N,N-diethylpyridine-2-carboxamide;methane is sourced from PubChem (CID 157065444), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).