(1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine

C133H166Br2Cl3F10N23O15S13 — CID 157066383

About (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine

(1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine (PubChem CID 157066383) has the molecular formula C133H166Br2Cl3F10N23O15S13 and a molecular weight of 3199.95 g/mol. Its IUPAC name is (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine.

Molecular Properties

• Compound Name: (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine
• PubChem CID: 157066383
• Molecular Formula: C133H166Br2Cl3F10N23O15S13
• Molecular Weight: 3199.95 g/mol
• Exact Mass: 3193.66
• IUPAC Name: (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine
• SMILES: CCN[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Br.CN(C)[C@@H]1CC=C(C(F)(F)F)C[C@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CN(C)[C@H]1CCCC[C@@H]1N1CCOc2cc(S(=O)(=O)Cc3nccs3)ccc21.CN(C)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2ncc(F)s2)cc1Cl.CN(C1CNC1)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2ccncn2)cc1Cl.CN[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Br.CN[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1C1CC1
• InChI: InChI=1S/C21H27ClFN5O2S.C20H26FN3O2S2.C20H27N3O3S2.C19H20ClF4N3O2S2.C18H23BrFN3O2S2.C18H22ClF2N3O2S2.C17H21BrFN3O2S2/c1-28(15-10-25-11-15)20-5-3-2-4-18(20)27-19-9-17(23)21(8-16(19)22)31(29,30)12-14-6-7-24-13-26-14;1-22-16-4-2-3-5-17(16)24-18-11-15(21)19(10-14(18)13-6-7-13)28(25,26)12-20-23-8-9-27-20;1-22(2)16-5-3-4-6-17(16)23-10-11-26-19-13-15(7-8-18(19)23)28(24,25)14-20-21-9-12-27-20;1-27(2)16-4-3-11(19(22,23)24)7-15(16)26-14-9-13(21)17(8-12(14)20)31(28,29)10-18-25-5-6-30-18;1-2-21-14-5-3-4-6-15(14)23-16-10-13(20)17(9-12(16)19)27(24,25)11-18-22-7-8-26-18;1-24(2)15-6-4-3-5-13(15)23-14-8-12(20)16(7-11(14)19)28(25,26)10-18-22-9-17(21)27-18;1-20-13-4-2-3-5-14(13)22-15-9-12(19)16(8-11(15)18)26(23,24)10-17-21-6-7-25-17/h6-9,13,15,18,20,25,27H,2-5,10-12H2,1H3;8-11,13,16-17,22,24H,2-7,12H2,1H3;7-9,12-13,16-17H,3-6,10-11,14H2,1-2H3;3,5-6,8-9,15-16,26H,4,7,10H2,1-2H3;7-10,14-15,21,23H,2-6,11H2,1H3;7-9,13,15,23H,3-6,10H2,1-2H3;6-9,13-14,20,22H,2-5,10H2,1H3/t18-,20-;2*16-,17-;15-,16-;14-,15-;13-,15-;13-,14-/m0001000/s1
• InChIKey: ABXPMCJBSJVAIX-OEOBZOHFSA-N
• XLogP: 27.68
• TPSA: 487.83 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 44
• Rotatable Bonds: 44
• Heavy Atoms: 199
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3199.95
LogP ≤ 5	27.68
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	44

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'isolated_alkene', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine?

The IUPAC name of (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine (CID 157066383) is (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine.

What is the SMILES notation for (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine?

The canonical SMILES for (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine is CCN[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Br.CN(C)[C@@H]1CC=C(C(F)(F)F)C[C@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CN(C)[C@H]1CCCC[C@@H]1N1CCOc2cc(S(=O)(=O)Cc3nccs3)ccc21.CN(C)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2ncc(F)s2)cc1Cl.CN(C1CNC1)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2ccncn2)cc1Cl.CN[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Br.CN[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1C1CC1.

What is the InChIKey of (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine?

The InChIKey is ABXPMCJBSJVAIX-OEOBZOHFSA-N. The full InChI is InChI=1S/C21H27ClFN5O2S.C20H26FN3O2S2.C20H27N3O3S2.C19H20ClF4N3O2S2.C18H23BrFN3O2S2.C18H22ClF2N3O2S2.C17H21BrFN3O2S2/c1-28(15-10-25-11-15)20-5-3-2-4-18(20)27-19-9-17(23)21(8-16(19)22)31(29,30)12-14-6-7-24-13-26-14;1-22-16-4-2-3-5-17(16)24-18-11-15(21)19(10-14(18)13-6-7-13)28(25,26)12-20-23-8-9-27-20;1-22(2)16-5-3-4-6-17(16)23-10-11-26-19-13-15(7-8-18(19)23)28(24,25)14-20-21-9-12-27-20;1-27(2)16-4-3-11(19(22,23)24)7-15(16)26-14-9-13(21)17(8-12(14)20)31(28,29)10-18-25-5-6-30-18;1-2-21-14-5-3-4-6-15(14)23-16-10-13(20)17(9-12(16)19)27(24,25)11-18-22-7-8-26-18;1-24(2)15-6-4-3-5-13(15)23-14-8-12(20)16(7-11(14)19)28(25,26)10-18-22-9-17(21)27-18;1-20-13-4-2-3-5-14(13)22-15-9-12(19)16(8-11(15)18)26(23,24)10-17-21-6-7-25-17/h6-9,13,15,18,20,25,27H,2-5,10-12H2,1H3;8-11,13,16-17,22,24H,2-7,12H2,1H3;7-9,12-13,16-17H,3-6,10-11,14H2,1-2H3;3,5-6,8-9,15-16,26H,4,7,10H2,1-2H3;7-10,14-15,21,23H,2-6,11H2,1H3;7-9,13,15,23H,3-6,10H2,1-2H3;6-9,13-14,20,22H,2-5,10H2,1H3/t18-,20-;2*16-,17-;15-,16-;14-,15-;13-,15-;13-,14-/m0001000/s1.

What are the key properties of (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine?

(1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine has a molecular weight of 3199.95 g/mol, XLogP of 27.68, 44 rotatable bonds, 10 hydrogen bond donors, and 44 hydrogen bond acceptors.

Where does this data come from?

All data for (1R,2R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohex-4-ene-1,2-diamine;trans-(1S,2S)-2-N-(azetidin-3-yl)-1-N-[2-chloro-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-ethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-bromo-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-chloro-5-fluoro-4-[(5-fluoro-1,3-thiazol-2-yl)methylsulfonyl]phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-N-[2-cyclopropyl-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N-methylcyclohexane-1,2-diamine;trans-(1S,2S)-N,N-dimethyl-2-[7-(1,3-thiazol-2-ylmethylsulfonyl)-2,3-dihydro-1,4-benzoxazin-4-yl]cyclohexan-1-amine is sourced from PubChem (CID 157066383), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).