2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol

C136H164FN41O6 — CID 157075745

About 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol

2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol (PubChem CID 157075745) has the molecular formula C136H164FN41O6 and a molecular weight of 2488.09 g/mol. Its IUPAC name is 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol.

Molecular Properties

• Compound Name: 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol
• PubChem CID: 157075745
• Molecular Formula: C136H164FN41O6
• Molecular Weight: 2488.09 g/mol
• Exact Mass: 2486.38
• IUPAC Name: 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol
• SMILES: CN(c1ncc(-c2ccc(-c3ccc4[nH]ncc4c3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1ncc(-c2ccc(-c3ccc4nccn4n3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1ncc(-c2ccc(-n3cc(F)cn3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.Cc1cnn(-c2ccc(-c3cnc(N(C)C4CC(C)(C)NC(C)(C)C4)nn3)c(O)c2)c1.Oc1cc(-c2cn[nH]c2)ccc1-c1cnc(N2CC3(CCCCC3)C2)nn1.Oc1cc(-c2cn[nH]c2)ccc1-c1cnc(N2CCC3(CCC3)CC2)nn1
• InChI: InChI=1S/C26H31N7O.C25H30N8O.C23H31N7O.C22H28FN7O.2C20H22N6O/c1-25(2)12-19(13-26(3,4)32-25)33(5)24-27-15-22(30-31-24)20-8-6-17(11-23(20)34)16-7-9-21-18(10-16)14-28-29-21;1-24(2)13-17(14-25(3,4)31-24)32(5)23-27-15-20(28-29-23)18-7-6-16(12-21(18)34)19-8-9-22-26-10-11-33(22)30-19;1-15-12-25-30(14-15)16-7-8-18(20(31)9-16)19-13-24-21(27-26-19)29(6)17-10-22(2,3)28-23(4,5)11-17;1-21(2)9-16(10-22(3,4)28-21)29(5)20-24-12-18(26-27-20)17-7-6-15(8-19(17)31)30-13-14(23)11-25-30;27-18-10-14(15-11-22-23-12-15)2-3-16(18)17-13-21-19(25-24-17)26-8-6-20(7-9-26)4-1-5-20;27-18-8-14(15-9-22-23-10-15)4-5-16(18)17-11-21-19(25-24-17)26-12-20(13-26)6-2-1-3-7-20/h6-11,14-15,19,32,34H,12-13H2,1-5H3,(H,28,29);6-12,15,17,31,34H,13-14H2,1-5H3;7-9,12-14,17,28,31H,10-11H2,1-6H3;6-8,11-13,16,28,31H,9-10H2,1-5H3;2-3,10-13,27H,1,4-9H2,(H,22,23);4-5,8-11,27H,1-3,6-7,12-13H2,(H,22,23)
• InChIKey: ACYMRGAZBWEPSY-UHFFFAOYSA-N
• XLogP: 21.84
• TPSA: 572.83 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 44
• Rotatable Bonds: 22
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2488.09
LogP ≤ 5	21.84
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	44

Frequently Asked Questions

What is the IUPAC name of 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol?

The IUPAC name of 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol (CID 157075745) is 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol.

What is the SMILES notation for 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol?

The canonical SMILES for 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol is CN(c1ncc(-c2ccc(-c3ccc4[nH]ncc4c3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1ncc(-c2ccc(-c3ccc4nccn4n3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1ncc(-c2ccc(-n3cc(F)cn3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.Cc1cnn(-c2ccc(-c3cnc(N(C)C4CC(C)(C)NC(C)(C)C4)nn3)c(O)c2)c1.Oc1cc(-c2cn[nH]c2)ccc1-c1cnc(N2CC3(CCCCC3)C2)nn1.Oc1cc(-c2cn[nH]c2)ccc1-c1cnc(N2CCC3(CCC3)CC2)nn1.

What is the InChIKey of 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol?

The InChIKey is ACYMRGAZBWEPSY-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H31N7O.C25H30N8O.C23H31N7O.C22H28FN7O.2C20H22N6O/c1-25(2)12-19(13-26(3,4)32-25)33(5)24-27-15-22(30-31-24)20-8-6-17(11-23(20)34)16-7-9-21-18(10-16)14-28-29-21;1-24(2)13-17(14-25(3,4)31-24)32(5)23-27-15-20(28-29-23)18-7-6-16(12-21(18)34)19-8-9-22-26-10-11-33(22)30-19;1-15-12-25-30(14-15)16-7-8-18(20(31)9-16)19-13-24-21(27-26-19)29(6)17-10-22(2,3)28-23(4,5)11-17;1-21(2)9-16(10-22(3,4)28-21)29(5)20-24-12-18(26-27-20)17-7-6-15(8-19(17)31)30-13-14(23)11-25-30;27-18-10-14(15-11-22-23-12-15)2-3-16(18)17-13-21-19(25-24-17)26-8-6-20(7-9-26)4-1-5-20;27-18-8-14(15-9-22-23-10-15)4-5-16(18)17-11-21-19(25-24-17)26-12-20(13-26)6-2-1-3-7-20/h6-11,14-15,19,32,34H,12-13H2,1-5H3,(H,28,29);6-12,15,17,31,34H,13-14H2,1-5H3;7-9,12-14,17,28,31H,10-11H2,1-6H3;6-8,11-13,16,28,31H,9-10H2,1-5H3;2-3,10-13,27H,1,4-9H2,(H,22,23);4-5,8-11,27H,1-3,6-7,12-13H2,(H,22,23).

What are the key properties of 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol?

2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol has a molecular weight of 2488.09 g/mol, XLogP of 21.84, 22 rotatable bonds, 13 hydrogen bond donors, and 44 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[3-(2-azaspiro[3.5]nonan-2-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;2-[3-(7-azaspiro[3.5]nonan-7-yl)-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)phenol;5-(4-fluoropyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-imidazo[1,2-b]pyridazin-6-yl-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(1H-indazol-5-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;5-(4-methylpyrazol-1-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol is sourced from PubChem (CID 157075745), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).