1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide

C95H86ClN25O5S10 — CID 157081018

About 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide

1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide (PubChem CID 157081018) has the molecular formula C95H86ClN25O5S10 and a molecular weight of 2014.03 g/mol. Its IUPAC name is 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide.

Molecular Properties

• Compound Name: 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide
• PubChem CID: 157081018
• Molecular Formula: C95H86ClN25O5S10
• Molecular Weight: 2014.03 g/mol
• Exact Mass: 2011.41
• IUPAC Name: 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide
• SMILES: CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4c(C)cccn34)cs2)s1.CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4cc(C)ccn34)cs2)s1.CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4ccc(C)cn34)cs2)s1.CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4cccc(C)n34)cs2)s1.Cc1ncccc1CC(=O)c1ccc(Nc2nc(-c3c(C)nc4c(Cl)cccn34)cs2)s1
• InChI: InChI=1S/C23H18ClN5OS2.4C18H17N5OS2/c1-13-15(5-3-9-25-13)11-18(30)19-7-8-20(32-19)28-23-27-17(12-31-23)21-14(2)26-22-16(24)6-4-10-29(21)22;1-10-4-6-14-20-11(2)16(23(14)8-10)12-9-25-18(21-12)22-15-7-5-13(26-15)17(24)19-3;1-10-6-7-23-14(8-10)20-11(2)16(23)12-9-25-18(21-12)22-15-5-4-13(26-15)17(24)19-3;1-10-5-4-8-23-15(11(2)20-16(10)23)12-9-25-18(21-12)22-14-7-6-13(26-14)17(24)19-3;1-10-5-4-6-14-20-11(2)16(23(10)14)12-9-25-18(21-12)22-15-8-7-13(26-15)17(24)19-3/h3-10,12H,11H2,1-2H3,(H,27,28);4*4-9H,1-3H3,(H,19,24)(H,21,22)
• InChIKey: ADNQRBLDZFMOGB-UHFFFAOYSA-N
• XLogP: 23.31
• TPSA: 357.46 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 36
• Rotatable Bonds: 22
• Heavy Atoms: 136
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2014.03
LogP ≤ 5	23.31
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide?

The IUPAC name of 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide (CID 157081018) is 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide.

What is the SMILES notation for 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide?

The canonical SMILES for 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide is CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4c(C)cccn34)cs2)s1.CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4cc(C)ccn34)cs2)s1.CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4ccc(C)cn34)cs2)s1.CNC(=O)c1ccc(Nc2nc(-c3c(C)nc4cccc(C)n34)cs2)s1.Cc1ncccc1CC(=O)c1ccc(Nc2nc(-c3c(C)nc4c(Cl)cccn34)cs2)s1.

What is the InChIKey of 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide?

The InChIKey is ADNQRBLDZFMOGB-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H18ClN5OS2.4C18H17N5OS2/c1-13-15(5-3-9-25-13)11-18(30)19-7-8-20(32-19)28-23-27-17(12-31-23)21-14(2)26-22-16(24)6-4-10-29(21)22;1-10-4-6-14-20-11(2)16(23(14)8-10)12-9-25-18(21-12)22-15-7-5-13(26-15)17(24)19-3;1-10-6-7-23-14(8-10)20-11(2)16(23)12-9-25-18(21-12)22-15-5-4-13(26-15)17(24)19-3;1-10-5-4-8-23-15(11(2)20-16(10)23)12-9-25-18(21-12)22-14-7-6-13(26-14)17(24)19-3;1-10-5-4-6-14-20-11(2)16(23(10)14)12-9-25-18(21-12)22-15-8-7-13(26-15)17(24)19-3/h3-10,12H,11H2,1-2H3,(H,27,28);4*4-9H,1-3H3,(H,19,24)(H,21,22).

What are the key properties of 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide?

1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide has a molecular weight of 2014.03 g/mol, XLogP of 23.31, 22 rotatable bonds, 9 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[5-[[4-(8-chloro-2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]thiophen-2-yl]-2-(2-methyl-3-pyridinyl)ethanone;5-[[4-(2,5-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,6-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide;5-[[4-(2,8-dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]-N-methylthiophene-2-carboxamide is sourced from PubChem (CID 157081018), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).