2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one

C145H113F12N33O7S — CID 157082955

IUPAC2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one
SMILESCN1Cc2cnc3ccc(-c4ccc(CO)nc4)nc3c2N(c2ccc(C(C)(C)C#N)cc2)C1=O.CN1Cc2cnc3ccc(-c4ccc5c(c4)C=NC5)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4ccsc4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4cn[nH]c4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4cnn(C)c4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.Cc1ccc(-c2ccc3ncc4c(c3n2)N(c2ccc(C(C)(C)C#N)cc2)C(=O)N(C)C4)cn1
InChIInChI=1S/C27H24N6O2.C27H24N6O.C26H18F3N5O.C22H17F3N6O.C22H15F3N4OS.C21H15F3N6O/c1-27(2,16-28)19-5-8-21(9-6-19)33-25-18(14-32(3)26(33)35)13-30-23-11-10-22(31-24(23)25)17-4-7-20(15-34)29-12-17;1-17-5-6-18(13-29-17)22-11-12-23-24(31-22)25-19(14-30-23)15-32(4)26(34)33(25)21-9-7-20(8-10-21)27(2,3)16-28;1-33-14-18-13-31-22-8-7-21(15-5-6-16-11-30-12-17(16)9-15)32-23(22)24(18)34(25(33)35)20-4-2-3-19(10-20)26(27,28)29;1-29-11-14-9-26-18-7-6-17(13-10-27-30(2)12-13)28-19(18)20(14)31(21(29)32)16-5-3-4-15(8-16)22(23,24)25;1-28-11-14-10-26-18-6-5-17(13-7-8-31-12-13)27-19(18)20(14)29(21(28)30)16-4-2-3-15(9-16)22(23,24)25;1-29-11-13-8-25-17-6-5-16(12-9-26-27-10-12)28-18(17)19(13)30(20(29)31)15-4-2-3-14(7-15)21(22,23)24/h4-13,34H,14-15H2,1-3H3;5-14H,15H2,1-4H3;2-10,12-13H,11,14H2,1H3;3-10,12H,11H2,1-2H3;2-10,12H,11H2,1H3;2-10H,11H2,1H3,(H,26,27)
InChIKeyADTLEAJTQMGPCU-UHFFFAOYSA-N
MW2689.77 g/mol
LogP31.72
Rot. Bonds15

About 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one

2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one (PubChem CID 157082955) has the molecular formula C145H113F12N33O7S and a molecular weight of 2689.77 g/mol. Its IUPAC name is 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one.

Molecular Properties

Compound Name2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one
PubChem CID157082955
Molecular FormulaC145H113F12N33O7S
Molecular Weight2689.77 g/mol
Exact Mass2687.90
IUPAC Name2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one
SMILESCN1Cc2cnc3ccc(-c4ccc(CO)nc4)nc3c2N(c2ccc(C(C)(C)C#N)cc2)C1=O.CN1Cc2cnc3ccc(-c4ccc5c(c4)C=NC5)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4ccsc4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4cn[nH]c4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4cnn(C)c4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.Cc1ccc(-c2ccc3ncc4c(c3n2)N(c2ccc(C(C)(C)C#N)cc2)C(=O)N(C)C4)cn1
InChIInChI=1S/C27H24N6O2.C27H24N6O.C26H18F3N5O.C22H17F3N6O.C22H15F3N4OS.C21H15F3N6O/c1-27(2,16-28)19-5-8-21(9-6-19)33-25-18(14-32(3)26(33)35)13-30-23-11-10-22(31-24(23)25)17-4-7-20(15-34)29-12-17;1-17-5-6-18(13-29-17)22-11-12-23-24(31-22)25-19(14-30-23)15-32(4)26(34)33(25)21-9-7-20(8-10-21)27(2,3)16-28;1-33-14-18-13-31-22-8-7-21(15-5-6-16-11-30-12-17(16)9-15)32-23(22)24(18)34(25(33)35)20-4-2-3-19(10-20)26(27,28)29;1-29-11-14-9-26-18-7-6-17(13-10-27-30(2)12-13)28-19(18)20(14)31(21(29)32)16-5-3-4-15(8-16)22(23,24)25;1-28-11-14-10-26-18-6-5-17(13-7-8-31-12-13)27-19(18)20(14)29(21(28)30)16-4-2-3-15(9-16)22(23,24)25;1-29-11-13-8-25-17-6-5-16(12-9-26-27-10-12)28-18(17)19(13)30(20(29)31)15-4-2-3-14(7-15)21(22,23)24/h4-13,34H,14-15H2,1-3H3;5-14H,15H2,1-4H3;2-10,12-13H,11,14H2,1H3;3-10,12H,11H2,1-2H3;2-10,12H,11H2,1H3;2-10H,11H2,1H3,(H,26,27)
InChIKeyADTLEAJTQMGPCU-UHFFFAOYSA-N
XLogP31.72
TPSA448.43 Ų
H-Bond Donors2
H-Bond Acceptors28
Rotatable Bonds15
Heavy Atoms198
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002689.77
LogP ≤ 531.72
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 1028

Analyze 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?
The IUPAC name of 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one (CID 157082955) is 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one.
What is the SMILES notation for 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?
The canonical SMILES for 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one is CN1Cc2cnc3ccc(-c4ccc(CO)nc4)nc3c2N(c2ccc(C(C)(C)C#N)cc2)C1=O.CN1Cc2cnc3ccc(-c4ccc5c(c4)C=NC5)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4ccsc4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4cn[nH]c4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.CN1Cc2cnc3ccc(-c4cnn(C)c4)nc3c2N(c2cccc(C(F)(F)F)c2)C1=O.Cc1ccc(-c2ccc3ncc4c(c3n2)N(c2ccc(C(C)(C)C#N)cc2)C(=O)N(C)C4)cn1.
What is the InChIKey of 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?
The InChIKey is ADTLEAJTQMGPCU-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H24N6O2.C27H24N6O.C26H18F3N5O.C22H17F3N6O.C22H15F3N4OS.C21H15F3N6O/c1-27(2,16-28)19-5-8-21(9-6-19)33-25-18(14-32(3)26(33)35)13-30-23-11-10-22(31-24(23)25)17-4-7-20(15-34)29-12-17;1-17-5-6-18(13-29-17)22-11-12-23-24(31-22)25-19(14-30-23)15-32(4)26(34)33(25)21-9-7-20(8-10-21)27(2,3)16-28;1-33-14-18-13-31-22-8-7-21(15-5-6-16-11-30-12-17(16)9-15)32-23(22)24(18)34(25(33)35)20-4-2-3-19(10-20)26(27,28)29;1-29-11-14-9-26-18-7-6-17(13-10-27-30(2)12-13)28-19(18)20(14)31(21(29)32)16-5-3-4-15(8-16)22(23,24)25;1-28-11-14-10-26-18-6-5-17(13-7-8-31-12-13)27-19(18)20(14)29(21(28)30)16-4-2-3-15(9-16)22(23,24)25;1-29-11-13-8-25-17-6-5-16(12-9-26-27-10-12)28-18(17)19(13)30(20(29)31)15-4-2-3-14(7-15)21(22,23)24/h4-13,34H,14-15H2,1-3H3;5-14H,15H2,1-4H3;2-10,12-13H,11,14H2,1H3;3-10,12H,11H2,1-2H3;2-10,12H,11H2,1H3;2-10H,11H2,1H3,(H,26,27).
What are the key properties of 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?
2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one has a molecular weight of 2689.77 g/mol, XLogP of 31.72, 15 rotatable bonds, 2 hydrogen bond donors, and 28 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[9-[6-(hydroxymethyl)-3-pyridinyl]-3-methyl-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]-2-methylpropanenitrile;9-(1H-isoindol-5-yl)-3-methyl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;2-methyl-2-[4-[3-methyl-9-(6-methyl-3-pyridinyl)-2-oxo-4H-pyrimido[5,4-c][1,5]naphthyridin-1-yl]phenyl]propanenitrile;3-methyl-9-(1-methylpyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-(1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;3-methyl-9-thiophen-3-yl-1-[3-(trifluoromethyl)phenyl]-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one is sourced from PubChem (CID 157082955), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).