8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine

C67H67F4N17O5 — CID 157085018

About 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine

8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine (PubChem CID 157085018) has the molecular formula C67H67F4N17O5 and a molecular weight of 1266.38 g/mol. Its IUPAC name is 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

• Compound Name: 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine
• PubChem CID: 157085018
• Molecular Formula: C67H67F4N17O5
• Molecular Weight: 1266.38 g/mol
• Exact Mass: 1265.54
• IUPAC Name: 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine
• SMILES: COc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)c(F)cn1.Cc1cn2c(NCc3c(F)ccc4c3CCCO4)ncc(-c3cc(C)nn3C)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cnn(CC(C)(C)O)c3)c2n1
• InChI: InChI=1S/C23H25FN6O2.C22H19F2N5O2.C22H23FN6O/c1-14-11-30-21(28-14)17(15-8-27-29(12-15)13-23(2,3)31)9-25-22(30)26-10-18-16-6-7-32-20(16)5-4-19(18)24;1-12-11-29-21(28-12)16(14-7-20(30-2)25-10-18(14)24)9-27-22(29)26-8-15-13-5-6-31-19(13)4-3-17(15)23;1-13-9-19(28(3)27-13)17-11-25-22(29-12-14(2)26-21(17)29)24-10-16-15-5-4-8-30-20(15)7-6-18(16)23/h4-5,8-9,11-12,31H,6-7,10,13H2,1-3H3,(H,25,26);3-4,7,9-11H,5-6,8H2,1-2H3,(H,26,27);6-7,9,11-12H,4-5,8,10H2,1-3H3,(H,24,25)
• InChIKey: ADZKDQWISLAPMT-UHFFFAOYSA-N
• XLogP: 11.11
• TPSA: 232.34 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 22
• Rotatable Bonds: 15
• Heavy Atoms: 93
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1266.38
LogP ≤ 5	11.11
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	22

Frequently Asked Questions

What is the IUPAC name of 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine?

The IUPAC name of 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine (CID 157085018) is 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine.

What is the SMILES notation for 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine?

The canonical SMILES for 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine is COc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)c(F)cn1.Cc1cn2c(NCc3c(F)ccc4c3CCCO4)ncc(-c3cc(C)nn3C)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cnn(CC(C)(C)O)c3)c2n1.

What is the InChIKey of 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine?

The InChIKey is ADZKDQWISLAPMT-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25FN6O2.C22H19F2N5O2.C22H23FN6O/c1-14-11-30-21(28-14)17(15-8-27-29(12-15)13-23(2,3)31)9-25-22(30)26-10-18-16-6-7-32-20(16)5-4-19(18)24;1-12-11-29-21(28-12)16(14-7-20(30-2)25-10-18(14)24)9-27-22(29)26-8-15-13-5-6-31-19(13)4-3-17(15)23;1-13-9-19(28(3)27-13)17-11-25-22(29-12-14(2)26-21(17)29)24-10-16-15-5-4-8-30-20(15)7-6-18(16)23/h4-5,8-9,11-12,31H,6-7,10,13H2,1-3H3,(H,25,26);3-4,7,9-11H,5-6,8H2,1-2H3,(H,26,27);6-7,9,11-12H,4-5,8,10H2,1-3H3,(H,24,25).

What are the key properties of 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine?

8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 1266.38 g/mol, XLogP of 11.11, 15 rotatable bonds, 4 hydrogen bond donors, and 22 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(2,5-dimethylpyrazol-3-yl)-N-[(6-fluoro-3,4-dihydro-2H-chromen-5-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(5-fluoro-2-methoxy-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 157085018), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).