N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide

C74H78N24O4 — CID 157090159

IUPACN-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide
SMILESCN1CCN(c2ccc(-c3nn(C)cc3NC(=O)c3cccc(-c4ccn[nH]4)n3)nc2)CC1.Cc1cncc(-c2cccc(C(=O)Nc3cn(C)nc3-c3ccc(N4CCN(C)CC4)cn3)n2)c1.Cc1cncc(-c2cccc(C(=O)Nc3cn(C)nc3-c3ccc(N4CCOCC4)cn3)n2)c1
InChIInChI=1S/C26H28N8O.C25H25N7O2.C23H25N9O/c1-18-13-19(15-27-14-18)21-5-4-6-23(29-21)26(35)30-24-17-33(3)31-25(24)22-8-7-20(16-28-22)34-11-9-32(2)10-12-34;1-17-12-18(14-26-13-17)20-4-3-5-22(28-20)25(33)29-23-16-31(2)30-24(23)21-7-6-19(15-27-21)32-8-10-34-11-9-32;1-30-10-12-32(13-11-30)16-6-7-19(24-14-16)22-21(15-31(2)29-22)27-23(33)20-5-3-4-17(26-20)18-8-9-25-28-18/h4-8,13-17H,9-12H2,1-3H3,(H,30,35);3-7,12-16H,8-11H2,1-2H3,(H,29,33);3-9,14-15H,10-13H2,1-2H3,(H,25,28)(H,27,33)
InChIKeyAEOLQUFNLJWVOU-UHFFFAOYSA-N
MW1367.60 g/mol
LogP8.86
Rot. Bonds15

About N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide

N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide (PubChem CID 157090159) has the molecular formula C74H78N24O4 and a molecular weight of 1367.60 g/mol. Its IUPAC name is N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide.

Molecular Properties

Compound NameN-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide
PubChem CID157090159
Molecular FormulaC74H78N24O4
Molecular Weight1367.60 g/mol
Exact Mass1366.66
IUPAC NameN-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide
SMILESCN1CCN(c2ccc(-c3nn(C)cc3NC(=O)c3cccc(-c4ccn[nH]4)n3)nc2)CC1.Cc1cncc(-c2cccc(C(=O)Nc3cn(C)nc3-c3ccc(N4CCN(C)CC4)cn3)n2)c1.Cc1cncc(-c2cccc(C(=O)Nc3cn(C)nc3-c3ccc(N4CCOCC4)cn3)n2)c1
InChIInChI=1S/C26H28N8O.C25H25N7O2.C23H25N9O/c1-18-13-19(15-27-14-18)21-5-4-6-23(29-21)26(35)30-24-17-33(3)31-25(24)22-8-7-20(16-28-22)34-11-9-32(2)10-12-34;1-17-12-18(14-26-13-17)20-4-3-5-22(28-20)25(33)29-23-16-31(2)30-24(23)21-7-6-19(15-27-21)32-8-10-34-11-9-32;1-30-10-12-32(13-11-30)16-6-7-19(24-14-16)22-21(15-31(2)29-22)27-23(33)20-5-3-4-17(26-20)18-8-9-25-28-18/h4-8,13-17H,9-12H2,1-3H3,(H,30,35);3-7,12-16H,8-11H2,1-2H3,(H,29,33);3-9,14-15H,10-13H2,1-2H3,(H,25,28)(H,27,33)
InChIKeyAEOLQUFNLJWVOU-UHFFFAOYSA-N
XLogP8.86
TPSA297.99 Ų
H-Bond Donors4
H-Bond Acceptors24
Rotatable Bonds15
Heavy Atoms102
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001367.60
LogP ≤ 58.86
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1024

Analyze N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

4-(5-butyl-2-pyridinyl)-1-methyl-N-[1-methyl-5-[[1-methyl-5-(2-morpholin-4-ylethylcarbamoyl)pyrrol-3-yl]carbamoyl]pyrrol-3-yl]pyrrole-2-carboxamide
CID 44351166
3-[4-fluoro-3-[2-oxo-2-[4-(3-phenyl-1H-pyrazol-4-yl)piperazin-1-yl]acetyl]-1H-pyrrolo[2,3-c]pyridin-7-yl]-N-(2-morpholinoethyl)-1H-pyrazole-5-carboxamide
CID 49770169
(S)-N-(5-(3-methyl-4-(oxetan-3-yl)piperazin-1-yl)-2-(trifluoromethyl)pyridin-3-yl)-6-(1H-pyrazol-4-yl)picolinamide
CID 165129716
N-[6-methyl-5-[4-[5-[4-(morpholin-4-ylmethyl)piperidin-1-yl]pyridin-3-yl]triazol-1-yl]pyridin-3-yl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 70902972
3-[4-fluoro-3-[2-oxo-2-[4-(3-phenylpyrazol-1-yl)piperazin-1-yl]acetyl]-1H-pyrrolo[2,3-c]pyridin-7-yl]-N-(2-morpholin-4-ylethyl)-1H-pyrazole-5-carboxamide
CID 89763243
N-[5-[5-[5-[4-[2-fluoro-2-[2-methyl-3-[5-[5-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-3-pyridinyl]-1,2-dihydrotriazol-3-yl]-5-[[4-(trifluoromethyl)pyridine-2-carbonyl]amino]pyridin-1-ium-1-yl]ethyl]piperazin-1-yl]-3-pyridinyl]-1,2-dihydrotriazol-3-yl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 90954439
N-[5-[amino-[2-[1-[2-[3-[4-(1,5-dimethylpyrazol-4-yl)-4,5-dihydrotriazol-1-yl]-5-[[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzoyl]amino]-2-pyridinyl]ethyl]-5-methylpyrazol-4-yl]-2-iminoethyl]amino]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 91114014
6-(3-fluoro-4-pyridinyl)-N-[1-[2-(2-methoxyethoxy)ethyl]-3-pyridin-2-ylpyrazol-4-yl]pyridine-2-carboxamide
CID 134450314
N-[5-[5-[1-[2-[3-[5-(1,5-dimethylpyrazol-4-yl)-1,2-dihydrotriazol-3-yl]-5-[[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzoyl]amino]pyridin-2-yl]ethyl]-5-methylpyrazol-4-yl]-1,2-dihydrotriazol-3-yl]-6-methylpyridin-3-yl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 143962297
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(pyrrolidin-1-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-(5-morpholin-4-yl-3-pyridinyl)-N-[6-(pyrrolidin-1-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-(5-piperidin-1-yl-3-pyridinyl)-N-[6-(pyrrolidin-1-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(pyrrolidin-1-ylmethyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
CID 157147381
5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-N-[4-(trifluoromethyl)phenyl]-1H-indazole-3-carboxamide;5-(5-morpholin-4-yl-3-pyridinyl)-N-[4-(trifluoromethyl)phenyl]-1H-indazole-3-carboxamide;5-(5-piperidin-1-yl-3-pyridinyl)-N-[4-(trifluoromethyl)phenyl]-1H-indazole-3-carboxamide;5-[5-(pyrrolidin-1-ylmethyl)-3-pyridinyl]-N-[4-(trifluoromethyl)phenyl]-1H-indazole-3-carboxamide
CID 157157559
bis(N-(6-methyl-3-pyridinyl)-5-[5-(piperidin-1-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide);5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-N-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-N-[4-(trifluoromethyl)phenyl]-1H-indazole-3-carboxamide;N-(6-phenyl-3-pyridinyl)-5-[5-(piperidin-1-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide
CID 157275842

Frequently Asked Questions

What is the IUPAC name of N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide?
The IUPAC name of N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide (CID 157090159) is N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide.
What is the SMILES notation for N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide?
The canonical SMILES for N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide is CN1CCN(c2ccc(-c3nn(C)cc3NC(=O)c3cccc(-c4ccn[nH]4)n3)nc2)CC1.Cc1cncc(-c2cccc(C(=O)Nc3cn(C)nc3-c3ccc(N4CCN(C)CC4)cn3)n2)c1.Cc1cncc(-c2cccc(C(=O)Nc3cn(C)nc3-c3ccc(N4CCOCC4)cn3)n2)c1.
What is the InChIKey of N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide?
The InChIKey is AEOLQUFNLJWVOU-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H28N8O.C25H25N7O2.C23H25N9O/c1-18-13-19(15-27-14-18)21-5-4-6-23(29-21)26(35)30-24-17-33(3)31-25(24)22-8-7-20(16-28-22)34-11-9-32(2)10-12-34;1-17-12-18(14-26-13-17)20-4-3-5-22(28-20)25(33)29-23-16-31(2)30-24(23)21-7-6-19(15-27-21)32-8-10-34-11-9-32;1-30-10-12-32(13-11-30)16-6-7-19(24-14-16)22-21(15-31(2)29-22)27-23(33)20-5-3-4-17(26-20)18-8-9-25-28-18/h4-8,13-17H,9-12H2,1-3H3,(H,30,35);3-7,12-16H,8-11H2,1-2H3,(H,29,33);3-9,14-15H,10-13H2,1-2H3,(H,25,28)(H,27,33).
What are the key properties of N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide?
N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide has a molecular weight of 1367.60 g/mol, XLogP of 8.86, 15 rotatable bonds, 4 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide;N-[1-methyl-3-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrazol-4-yl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide;N-[1-methyl-3-(5-morpholin-4-yl-2-pyridinyl)pyrazol-4-yl]-6-(5-methyl-3-pyridinyl)pyridine-2-carboxamide is sourced from PubChem (CID 157090159), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).