8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid

C202H239F7N38O13 — CID 157093276

IUPAC8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid
SMILESCC(C)n1ccc2c(N3CC4(CCC(c5ccccc5)(N(C)C)CC4)NC3=O)cccc21.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1=CCc3ccccc31)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc3c1ccn3C)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccc(C(N)=O)cc3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ncc(C#N)cc1F)C(=O)N2.Cc1cc(C#N)cnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.Cc1cc(C(F)(F)F)ncc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC(=O)N2CCCC2)C1=O.Cc1cc(C(N)=O)cnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.O=C(O)C(F)(F)F
InChIInChI=1S/C29H36F3N5O2.C27H30N6O2.C27H34N4O.C25H29N3O.C24H29N5O.C23H29N5O2.C23H27N5O.C22H24FN5O.C2HF3O2/c1-21-17-24(29(30,31)32)33-18-23(21)36-20-27(37(26(36)39)19-25(38)35-15-7-8-16-35)11-13-28(14-12-27,34(2)3)22-9-5-4-6-10-22;1-32(2)27(21-6-4-3-5-7-21)14-12-26(13-15-27)18-33(25(35)31-26)22-16-29-24(30-17-22)20-10-8-19(9-11-20)23(28)34;1-20(2)30-18-13-22-23(30)11-8-12-24(22)31-19-26(28-25(31)32)14-16-27(17-15-26,29(3)4)21-9-6-5-7-10-21;1-27(2)25(20-9-4-3-5-10-20)16-14-24(15-17-25)18-28(23(29)26-24)22-13-12-19-8-6-7-11-21(19)22;1-27(2)24(18-7-5-4-6-8-18)13-11-23(12-14-24)17-29(22(30)26-23)20-9-15-25-21-19(20)10-16-28(21)3;1-16-13-17(19(24)29)14-25-20(16)28-15-22(26-21(28)30)9-11-23(12-10-22,27(2)3)18-7-5-4-6-8-18;1-17-13-18(14-24)15-25-20(17)28-16-22(26-21(28)29)9-11-23(12-10-22,27(2)3)19-7-5-4-6-8-19;1-27(2)22(17-6-4-3-5-7-17)10-8-21(9-11-22)15-28(20(29)26-21)19-18(23)12-16(13-24)14-25-19;3-2(4,5)1(6)7/h4-6,9-10,17-18H,7-8,11-16,19-20H2,1-3H3;3-11,16-17H,12-15,18H2,1-2H3,(H2,28,34)(H,31,35);5-13,18,20H,14-17,19H2,1-4H3,(H,28,32);3-11,13H,12,14-18H2,1-2H3,(H,26,29);4-10,15-16H,11-14,17H2,1-3H3,(H,26,30);4-8,13-14H,9-12,15H2,1-3H3,(H2,24,29)(H,26,30);4-8,13,15H,9-12,16H2,1-3H3,(H,26,29);3-7,12,14H,8-11,15H2,1-2H3,(H,26,29);(H,6,7)
InChIKeyBXINWHCYDSHRMS-UHFFFAOYSA-N
MW3540.37 g/mol
LogP32.73
Rot. Bonds30

About 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid

8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid (PubChem CID 157093276) has the molecular formula C202H239F7N38O13 and a molecular weight of 3540.37 g/mol. Its IUPAC name is 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid.

Molecular Properties

Compound Name8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid
PubChem CID157093276
Molecular FormulaC202H239F7N38O13
Molecular Weight3540.37 g/mol
Exact Mass3537.91
IUPAC Name8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid
SMILESCC(C)n1ccc2c(N3CC4(CCC(c5ccccc5)(N(C)C)CC4)NC3=O)cccc21.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1=CCc3ccccc31)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc3c1ccn3C)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccc(C(N)=O)cc3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ncc(C#N)cc1F)C(=O)N2.Cc1cc(C#N)cnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.Cc1cc(C(F)(F)F)ncc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC(=O)N2CCCC2)C1=O.Cc1cc(C(N)=O)cnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.O=C(O)C(F)(F)F
InChIInChI=1S/C29H36F3N5O2.C27H30N6O2.C27H34N4O.C25H29N3O.C24H29N5O.C23H29N5O2.C23H27N5O.C22H24FN5O.C2HF3O2/c1-21-17-24(29(30,31)32)33-18-23(21)36-20-27(37(26(36)39)19-25(38)35-15-7-8-16-35)11-13-28(14-12-27,34(2)3)22-9-5-4-6-10-22;1-32(2)27(21-6-4-3-5-7-21)14-12-26(13-15-27)18-33(25(35)31-26)22-16-29-24(30-17-22)20-10-8-19(9-11-20)23(28)34;1-20(2)30-18-13-22-23(30)11-8-12-24(22)31-19-26(28-25(31)32)14-16-27(17-15-26,29(3)4)21-9-6-5-7-10-21;1-27(2)25(20-9-4-3-5-10-20)16-14-24(15-17-25)18-28(23(29)26-24)22-13-12-19-8-6-7-11-21(19)22;1-27(2)24(18-7-5-4-6-8-18)13-11-23(12-14-24)17-29(22(30)26-23)20-9-15-25-21-19(20)10-16-28(21)3;1-16-13-17(19(24)29)14-25-20(16)28-15-22(26-21(28)30)9-11-23(12-10-22,27(2)3)18-7-5-4-6-8-18;1-17-13-18(14-24)15-25-20(17)28-16-22(26-21(28)29)9-11-23(12-10-22,27(2)3)19-7-5-4-6-8-19;1-27(2)22(17-6-4-3-5-7-17)10-8-21(9-11-22)15-28(20(29)26-21)19-18(23)12-16(13-24)14-25-19;3-2(4,5)1(6)7/h4-6,9-10,17-18H,7-8,11-16,19-20H2,1-3H3;3-11,16-17H,12-15,18H2,1-2H3,(H2,28,34)(H,31,35);5-13,18,20H,14-17,19H2,1-4H3,(H,28,32);3-11,13H,12,14-18H2,1-2H3,(H,26,29);4-10,15-16H,11-14,17H2,1-3H3,(H,26,30);4-8,13-14H,9-12,15H2,1-3H3,(H2,24,29)(H,26,30);4-8,13,15H,9-12,16H2,1-3H3,(H,26,29);3-7,12,14H,8-11,15H2,1-2H3,(H,26,29);(H,6,7)
InChIKeyBXINWHCYDSHRMS-UHFFFAOYSA-N
XLogP32.73
TPSA567.31 Ų
H-Bond Donors10
H-Bond Acceptors31
Rotatable Bonds30
Heavy Atoms260
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003540.37
LogP ≤ 532.73
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1031

Analyze 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid with MolForge

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Related Compounds

4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(5-methyl-2-pyridin-3-ylpyrrolo[3,2-d]pyrimidin-4-yl)amino]benzamide;4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[(5-methyl-2-pyridin-3-ylpyrrolo[3,2-d]pyrimidin-4-yl)amino]benzamide;2-[4-methyl-3-[(5-methyl-2-pyridin-4-ylpyrrolo[3,2-d]pyrimidin-4-yl)amino]phenyl]-1-[3-(trifluoromethyl)phenyl]ethanone;4-methyl-3-[(5-methyl-2-pyridin-3-ylpyrrolo[3,2-d]pyrimidin-4-yl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide;4-methyl-3-[(5-methyl-2-pyridin-4-ylpyrrolo[3,2-d]pyrimidin-4-yl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide
CID 157053327
5-(3,3-dimethyl-2-oxo-1-pyridin-2-ylindol-4-yl)-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-(3,3-dimethyl-2-oxo-1-pyridin-3-ylindol-4-yl)-N-(5-methyl-2-pyridinyl)-2-(trifluoromethyl)pyridine-3-carboxamide;5-(3,3-dimethyl-2-oxo-1-pyridin-3-ylindol-4-yl)-N-phenyl-2-(trifluoromethyl)pyridine-3-carboxamide;5-(3,3-dimethyl-2-oxo-1-pyrimidin-4-ylindol-4-yl)-N-(3-fluoro-4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide
CID 157096621
5-[3-(4-cyano-2-pyridinyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(1-methylimidazol-4-yl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-5-[3-(1-methylimidazol-4-yl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-5-[3-(3-methyltriazol-4-yl)imidazo[1,5-a]pyridin-8-yl]-2-(trifluoromethyl)benzamide
CID 157212945
1H-indol-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;tetrakis((6-methyl-1H-pyrrolo[3,2-b]pyridin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);1H-pyrrolo[2,3-b]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-pyrrolo[3,2-b]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-pyrrolo[2,3-c]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 157255418
N-[2-fluoro-5-(trifluoromethyl)phenyl]-4-methyl-3-[(4-pyridin-3-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)methyl]benzamide;4-methyl-N-[3-methyl-5-(4-methylimidazol-1-yl)phenyl]-3-[(4-pyridin-3-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)methyl]benzamide;4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)methyl]benzamide;4-methyl-N-[2-methyl-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)methyl]benzamide
CID 157294126
1-ethyl-5-fluoro-N-(5-fluoro-3-pyridinyl)indole-3-carboxamide;1-(1-ethyl-5-fluoroindol-3-yl)-2-[6-(trifluoromethyl)-3-pyridinyl]ethanone;1-(1-ethyl-5-fluoroindol-3-yl)-2-[2-(trifluoromethyl)pyrimidin-4-yl]ethanone;1-ethyl-5-fluoro-N-[6-(trifluoromethyl)pyrimidin-4-yl]indole-3-carboxamide;5-fluoro-N-(5-fluoro-3-pyridinyl)-1-propan-2-ylindole-3-carboxamide;5-fluoro-1-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]indole-3-carboxamide
CID 157300408
2-[[6-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-3-pyridinyl]methylamino]-5-(1,1-difluoroethyl)-N-(4-fluorophenyl)pyridine-3-carboxamide;3-[[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]methylamino]-6-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]pyrazine-2-carboxamide;3-[[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]methylamino]-6-(1,1-difluoroethyl)-N-(4-fluorophenyl)pyrazine-2-carboxamide;2-[[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]methylamino]-N-(4-fluoro-3-methylphenyl)-5-(trifluoromethyl)pyridine-3-carboxamide;3-[[4-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]methylamino]-6-cyano-N-(4-methylphenyl)pyrazine-2-carboxamide
CID 157447320
5-(3,3-dimethyl-2-oxo-1-pyridin-3-ylindol-4-yl)-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(3-fluoro-4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;5-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[1-(5-fluoro-3-pyridinyl)-3,3-dimethyl-2-oxoindol-4-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide
CID 157478017
5-(3,3-dimethyl-2-oxo-1-pyridin-2-ylpyrrolo[2,3-b]pyridin-4-yl)-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;bis(5-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-pyridin-3-yl-2-(trifluoromethyl)benzamide);5-[3,3-dimethyl-2-oxo-1-(pyrimidin-2-ylmethyl)indol-4-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide
CID 157493857
5-[3-(3-cyano-2-pyridinyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-5-[3-(1-methylimidazol-4-yl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-5-(3-pyridazin-3-ylimidazo[1,5-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-quinolin-4-ylimidazo[1,5-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
CID 157565495
CID 157708815
CID 157708815
5-(3,3-dimethyl-2-oxo-1-pyridin-2-ylindol-4-yl)-2-methyl-N-(4-methylphenyl)benzamide;5-(3,3-dimethyl-2-oxo-1-pyridin-2-ylindol-4-yl)-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;5-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-phenyl-2-(trifluoromethyl)benzamide
CID 158280411

Frequently Asked Questions

What is the IUPAC name of 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid?
The IUPAC name of 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid (CID 157093276) is 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid.
What is the SMILES notation for 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid?
The canonical SMILES for 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid is CC(C)n1ccc2c(N3CC4(CCC(c5ccccc5)(N(C)C)CC4)NC3=O)cccc21.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1=CCc3ccccc31)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc3c1ccn3C)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccc(C(N)=O)cc3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ncc(C#N)cc1F)C(=O)N2.Cc1cc(C#N)cnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.Cc1cc(C(F)(F)F)ncc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC(=O)N2CCCC2)C1=O.Cc1cc(C(N)=O)cnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.O=C(O)C(F)(F)F.
What is the InChIKey of 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid?
The InChIKey is BXINWHCYDSHRMS-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H36F3N5O2.C27H30N6O2.C27H34N4O.C25H29N3O.C24H29N5O.C23H29N5O2.C23H27N5O.C22H24FN5O.C2HF3O2/c1-21-17-24(29(30,31)32)33-18-23(21)36-20-27(37(26(36)39)19-25(38)35-15-7-8-16-35)11-13-28(14-12-27,34(2)3)22-9-5-4-6-10-22;1-32(2)27(21-6-4-3-5-7-21)14-12-26(13-15-27)18-33(25(35)31-26)22-16-29-24(30-17-22)20-10-8-19(9-11-20)23(28)34;1-20(2)30-18-13-22-23(30)11-8-12-24(22)31-19-26(28-25(31)32)14-16-27(17-15-26,29(3)4)21-9-6-5-7-10-21;1-27(2)25(20-9-4-3-5-10-20)16-14-24(15-17-25)18-28(23(29)26-24)22-13-12-19-8-6-7-11-21(19)22;1-27(2)24(18-7-5-4-6-8-18)13-11-23(12-14-24)17-29(22(30)26-23)20-9-15-25-21-19(20)10-16-28(21)3;1-16-13-17(19(24)29)14-25-20(16)28-15-22(26-21(28)30)9-11-23(12-10-22,27(2)3)18-7-5-4-6-8-18;1-17-13-18(14-24)15-25-20(17)28-16-22(26-21(28)29)9-11-23(12-10-22,27(2)3)19-7-5-4-6-8-19;1-27(2)22(17-6-4-3-5-7-17)10-8-21(9-11-22)15-28(20(29)26-21)19-18(23)12-16(13-24)14-25-19;3-2(4,5)1(6)7/h4-6,9-10,17-18H,7-8,11-16,19-20H2,1-3H3;3-11,16-17H,12-15,18H2,1-2H3,(H2,28,34)(H,31,35);5-13,18,20H,14-17,19H2,1-4H3,(H,28,32);3-11,13H,12,14-18H2,1-2H3,(H,26,29);4-10,15-16H,11-14,17H2,1-3H3,(H,26,30);4-8,13-14H,9-12,15H2,1-3H3,(H2,24,29)(H,26,30);4-8,13,15H,9-12,16H2,1-3H3,(H,26,29);3-7,12,14H,8-11,15H2,1-2H3,(H,26,29);(H,6,7).
What are the key properties of 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid?
8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid has a molecular weight of 3540.37 g/mol, XLogP of 32.73, 30 rotatable bonds, 10 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for 8-(dimethylamino)-3-(3H-inden-1-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-fluoropyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carbonitrile;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylpyridine-3-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(1-propan-2-ylindol-4-yl)-1,3-diazaspiro[4.5]decan-2-one;2,2,2-trifluoroacetic acid is sourced from PubChem (CID 157093276), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).